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{{STRUCTURE_1mdr|  PDB=1mdr  |  SCENE=  }}
===THE ROLE OF LYSINE 166 IN THE MECHANISM OF MANDELATE RACEMASE FROM PSEUDOMONAS PUTIDA: MECHANISTIC AND CRYSTALLOGRAPHIC EVIDENCE FOR STEREOSPECIFIC ALKYLATION BY (R)-ALPHA-PHENYLGLYCIDATE===
{{ABSTRACT_PUBMED_8292591}}


==About this Structure==
==THE ROLE OF LYSINE 166 IN THE MECHANISM OF MANDELATE RACEMASE FROM PSEUDOMONAS PUTIDA: MECHANISTIC AND CRYSTALLOGRAPHIC EVIDENCE FOR STEREOSPECIFIC ALKYLATION BY (R)-ALPHA-PHENYLGLYCIDATE==
[[1mdr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MDR OCA].  
<StructureSection load='1mdr' size='340' side='right'caption='[[1mdr]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1mdr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MDR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MDR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=APG:ATROLACTIC+ACID+(2-PHENYL-LACTIC+ACID)'>APG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mdr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mdr OCA], [https://pdbe.org/1mdr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mdr RCSB], [https://www.ebi.ac.uk/pdbsum/1mdr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mdr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MANR_PSEPU MANR_PSEPU]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/md/1mdr_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mdr ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Mandelate racemase|Mandelate racemase]]
*[[Mandelate racemase|Mandelate racemase]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:008292591</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Mandelate racemase]]
[[Category: Pseudomonas putida]]
[[Category: Pseudomonas putida]]
[[Category: Fujita, S.]]
[[Category: Fujita S]]
[[Category: Gerlt, J A.]]
[[Category: Gerlt JA]]
[[Category: Kenyon, G L.]]
[[Category: Kenyon GL]]
[[Category: Koo, C W.]]
[[Category: Koo CW]]
[[Category: Kozarich, J W.]]
[[Category: Kozarich JW]]
[[Category: Landro, J A.]]
[[Category: Landro JA]]
[[Category: Neidhart, D J.]]
[[Category: Neidhart DJ]]
[[Category: Petsko, G A.]]
[[Category: Petsko GA]]
[[Category: Shah, V J.]]
[[Category: Shah VJ]]
[[Category: Racemase]]

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