1m6n: Difference between revisions

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[[Image:1m6n.png|left|200px]]


{{STRUCTURE_1m6n|  PDB=1m6n  |  SCENE=  }}
==Crystal structure of the SecA translocation ATPase from Bacillus subtilis==
 
<StructureSection load='1m6n' size='340' side='right'caption='[[1m6n]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
===Crystal structure of the SecA translocation ATPase from Bacillus subtilis===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1m6n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M6N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M6N FirstGlance]. <br>
{{ABSTRACT_PUBMED_12242434}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m6n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m6n OCA], [https://pdbe.org/1m6n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m6n RCSB], [https://www.ebi.ac.uk/pdbsum/1m6n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m6n ProSAT]</span></td></tr>
[[1m6n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M6N OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/SECA_BACSU SECA_BACSU] Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane (By similarity).[HAMAP-Rule:MF_01382]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m6/1m6n_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m6n ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Preprotein translocase 3D structures|Preprotein translocase 3D structures]]
*[[SecA|SecA]]
*[[SecA|SecA]]
*[[SecA PBD motions|SecA PBD motions]]
__TOC__
 
</StructureSection>
==Reference==
<ref group="xtra">PMID:012242434</ref><ref group="xtra">PMID:016754988</ref><references group="xtra"/>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Deisenhofer, J.]]
[[Category: Large Structures]]
[[Category: Fak, J J.]]
[[Category: Deisenhofer J]]
[[Category: Henry, L.]]
[[Category: Fak JJ]]
[[Category: Hunt, J F.]]
[[Category: Henry L]]
[[Category: McNicholas, P.]]
[[Category: Hunt JF]]
[[Category: Oliver, D B.]]
[[Category: McNicholas P]]
[[Category: Weinkauf, S.]]
[[Category: Oliver DB]]
[[Category: Atpase]]
[[Category: Weinkauf S]]
[[Category: Helicase family structure]]
[[Category: Mechanochemisty]]
[[Category: Protein translocation]]
[[Category: Protein transport]]
[[Category: Transmembrane transport]]

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