1m4y: Difference between revisions

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[[Image:1m4y.png|left|200px]]


{{STRUCTURE_1m4y|  PDB=1m4y  |  SCENE=  }}
==Crystal structure of HslV from Thermotoga maritima==
 
<StructureSection load='1m4y' size='340' side='right'caption='[[1m4y]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
===Crystal structure of HslV from Thermotoga maritima===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1m4y]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M4Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M4Y FirstGlance]. <br>
{{ABSTRACT_PUBMED_12646382}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m4y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m4y OCA], [https://pdbe.org/1m4y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m4y RCSB], [https://www.ebi.ac.uk/pdbsum/1m4y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m4y ProSAT]</span></td></tr>
[[1m4y]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M4Y OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/HSLV_THEMA HSLV_THEMA] Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.<ref>PMID:12646382</ref>  
<ref group="xtra">PMID:012646382</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m4/1m4y_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m4y ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
[[Category: Azim, M K.]]
[[Category: Azim MK]]
[[Category: Bochtler, M B.]]
[[Category: Bochtler MB]]
[[Category: Hartmann, C.]]
[[Category: Hartmann C]]
[[Category: Huber, R.]]
[[Category: Huber R]]
[[Category: Ramachandran, R.]]
[[Category: Ramachandran R]]
[[Category: Song, H K.]]
[[Category: Song HK]]
[[Category: Hydrolase]]
[[Category: N-terminal catalytic threonine residue]]

Latest revision as of 10:39, 14 February 2024

Crystal structure of HslV from Thermotoga maritimaCrystal structure of HslV from Thermotoga maritima

Structural highlights

1m4y is a 3 chain structure with sequence from Thermotoga maritima. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.1Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HSLV_THEMA Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Song HK, Bochtler M, Azim MK, Hartmann C, Huber R, Ramachandran R. Isolation and characterization of the prokaryotic proteasome homolog HslVU (ClpQY) from Thermotoga maritima and the crystal structure of HslV. Biophys Chem. 2003;100(1-3):437-52. PMID:12646382

1m4y, resolution 2.10Å

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