1m1e: Difference between revisions

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-{{Seed}}
-[[Image:1m1e.png|left|200px]]
-<!--
+==Beta-catenin armadillo repeat domain bound to ICAT==
-The line below this paragraph, containing "STRUCTURE_1m1e", creates the "Structure Box" on the page.
+<StructureSection load='1m1e' size='340' side='right'caption='[[1m1e]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1m1e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M1E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M1E FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m1e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m1e OCA], [https://pdbe.org/1m1e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m1e RCSB], [https://www.ebi.ac.uk/pdbsum/1m1e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m1e ProSAT]</span></td></tr>
-{{STRUCTURE_1m1e|  PDB=1m1e  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CNBP1_HUMAN CNBP1_HUMAN] Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m1/1m1e_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m1e ConSurf].
+<div style="clear:both"></div>
-===Beta-catenin armadillo repeat domain bound to ICAT===
+==See Also==
+*[[Catenin 3D structures|Catenin 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_12408825}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 12408825 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_12408825}}
-==About this Structure==
-M1E is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M1E OCA].
-==Reference==
-ICAT inhibits beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules., Daniels DL, Weis WI, Mol Cell. 2002 Sep;10(3):573-84. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12408825 12408825]
 [[Category: Homo sapiens]]
+[[Category: Large Structures]]
 [[Category: Mus musculus]]
-[[Category: Protein complex]]
+[[Category: Daniels DL]]
-[[Category: Daniels, D L.]]
+[[Category: Weis WI]]
-[[Category: Weis, W I.]]
-[[Category: Armadillo repeat]]
-[[Category: Cell adhesion]]
-[[Category: Cytoskeleton]]
-[[Category: Transciption factor]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  2 23:00:37 2008''