1lrn: Difference between revisions

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[[Image:1lrn.png|left|200px]]


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==Aquifex aeolicus KDO8P synthase H185G mutant in complex with Cadmium==
The line below this paragraph, containing "STRUCTURE_1lrn", creates the "Structure Box" on the page.
<StructureSection load='1lrn' size='340' side='right'caption='[[1lrn]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1lrn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LRN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LRN FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
{{STRUCTURE_1lrn|  PDB=1lrn |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lrn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lrn OCA], [https://pdbe.org/1lrn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lrn RCSB], [https://www.ebi.ac.uk/pdbsum/1lrn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lrn ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KDSA_AQUAE KDSA_AQUAE]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lr/1lrn_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lrn ConSurf].
<div style="clear:both"></div>


===Aquifex aeolicus KDO8P synthase H185G mutant in complex with Cadmium===
==See Also==
 
*[[Kdo-8-phosphate synthase|Kdo-8-phosphate synthase]]
 
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_12441100}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 12441100 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12441100}}
 
==About this Structure==
1LRN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LRN OCA].
 
==Reference==
Function of His185 in Aquifex aeolicus 3-deoxy-D-manno-octulosonate 8-phosphate synthase., Wang J, Duewel HS, Stuckey JA, Woodard RW, Gatti DL, J Mol Biol. 2002 Nov 22;324(2):205-14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12441100 12441100]
[[Category: 3-deoxy-8-phosphooctulonate synthase]]
[[Category: Aquifex aeolicus]]
[[Category: Aquifex aeolicus]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Duewel, H S.]]
[[Category: Duewel HS]]
[[Category: Gatti, D L.]]
[[Category: Gatti DL]]
[[Category: Stuckey, J A.]]
[[Category: Stuckey JA]]
[[Category: Wang, J.]]
[[Category: Wang J]]
[[Category: Woodard, R W.]]
[[Category: Woodard RW]]
[[Category: Kdo]]
[[Category: Kdo8p]]
[[Category: Kdo8p]]
 
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