1lep: Difference between revisions

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-{{Seed}}
-[[Image:1lep.png|left|200px]]
-<!--
+==THREE-DIMENSIONAL STRUCTURE OF THE IMMUNODOMINANT HEAT-SHOCK PROTEIN CHAPERONIN-10 OF MYCOBACTERIUM LEPRAE==
-The line below this paragraph, containing "STRUCTURE_1lep", creates the "Structure Box" on the page.
+<StructureSection load='1lep' size='340' side='right'caption='[[1lep]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1lep]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_leprae Mycobacterium leprae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LEP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LEP FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lep OCA], [https://pdbe.org/1lep PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lep RCSB], [https://www.ebi.ac.uk/pdbsum/1lep PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lep ProSAT]</span></td></tr>
-{{STRUCTURE_1lep|  PDB=1lep  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CH10_MYCLE CH10_MYCLE] Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.[HAMAP-Rule:MF_00580]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/le/1lep_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lep ConSurf].
+<div style="clear:both"></div>
-===THREE-DIMENSIONAL STRUCTURE OF THE IMMUNODOMINANT HEAT-SHOCK PROTEIN CHAPERONIN-10 OF MYCOBACTERIUM LEPRAE===
+==See Also==
+*[[Chaperonin 3D structures|Chaperonin 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_8539620}}, adds the Publication Abstract to the page
+[[Category: Large Structures]]
-(as it appears on PubMed at http://www.pubmed.gov), where 8539620 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_8539620}}
-==About this Structure==
-LEP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_leprae Mycobacterium leprae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LEP OCA].
-==Reference==
-Structure of the heat shock protein chaperonin-10 of Mycobacterium leprae., Mande SC, Mehra V, Bloom BR, Hol WG, Science. 1996 Jan 12;271(5246):203-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8539620 8539620]
 [[Category: Mycobacterium leprae]]
-[[Category: Single protein]]
+[[Category: Hol WGJ]]
-[[Category: Hol, W G.J.]]
+[[Category: Mande SC]]
-[[Category: Mande, S C.]]
-[[Category: Antigen]]
-[[Category: Chaperone]]
-[[Category: Heat shock]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 05:22:06 2008''