1lc3: Difference between revisions

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[[Image:1lc3.png|left|200px]]


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==Crystal Structure of a Biliverdin Reductase Enzyme-Cofactor Complex==
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<StructureSection load='1lc3' size='340' side='right'caption='[[1lc3]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1lc3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LC3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LC3 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
{{STRUCTURE_1lc3|  PDB=1lc3  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lc3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lc3 OCA], [https://pdbe.org/1lc3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lc3 RCSB], [https://www.ebi.ac.uk/pdbsum/1lc3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lc3 ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of a Biliverdin Reductase Enzyme-Cofactor Complex===
== Function ==
 
[https://www.uniprot.org/uniprot/BIEA_RAT BIEA_RAT] Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor.
 
== Evolutionary Conservation ==
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==About this Structure==
  </jmolCheckbox>
1LC3 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LC3 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lc3 ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
<ref group="xtra">PMID:12079357</ref><references group="xtra"/>
</StructureSection>
[[Category: Biliverdin reductase]]
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Hill, C P.]]
[[Category: Hill CP]]
[[Category: Maines, M D.]]
[[Category: Maines MD]]
[[Category: McCoubrey, W.]]
[[Category: McCoubrey W]]
[[Category: Phillips, J D.]]
[[Category: Phillips JD]]
[[Category: Whitby, F G.]]
[[Category: Whitby FG]]
[[Category: Bile pigment]]
[[Category: Bilirubin]]
[[Category: Biliverdin reductase]]
[[Category: Heme]]
[[Category: Nadh]]
[[Category: Tetrapyrrole]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:33:27 2009''

Latest revision as of 10:31, 14 February 2024

Crystal Structure of a Biliverdin Reductase Enzyme-Cofactor ComplexCrystal Structure of a Biliverdin Reductase Enzyme-Cofactor Complex

Structural highlights

1lc3 is a 1 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.5Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

BIEA_RAT Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1lc3, resolution 1.50Å

Drag the structure with the mouse to rotate

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OCA
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