1lbg: Difference between revisions

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[[Image:1lbg.png|left|200px]]


{{STRUCTURE_1lbg|  PDB=1lbg  |  SCENE=  }}
==LACTOSE OPERON REPRESSOR BOUND TO 21-BASE PAIR SYMMETRIC OPERATOR DNA, ALPHA CARBONS ONLY==
 
<StructureSection load='1lbg' size='340' side='right'caption='[[1lbg]], [[Resolution|resolution]] 4.80&Aring;' scene=''>
===LACTOSE OPERON REPRESSOR BOUND TO 21-BASE PAIR SYMMETRIC OPERATOR DNA, ALPHA CARBONS ONLY===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1lbg]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LBG FirstGlance]. <br>
{{ABSTRACT_PUBMED_8638105}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.8&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lbg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lbg OCA], [https://pdbe.org/1lbg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lbg RCSB], [https://www.ebi.ac.uk/pdbsum/1lbg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lbg ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1lbg]] is a 8 chain structure of [[Lac repressor]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBG OCA].  
== Function ==
[https://www.uniprot.org/uniprot/LACI_ECOLI LACI_ECOLI] Repressor of the lactose operon. Binds allolactose as an inducer.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lb/1lbg_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lbg ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Lac repressor|Lac repressor]]
*[[Lac repressor|Lac repressor]]
*[[Regulation of Gene Expression|Regulation of Gene Expression]]
__TOC__
 
</StructureSection>
==Reference==
<ref group="xtra">PMID:008638105</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Chang, G.]]
[[Category: Large Structures]]
[[Category: Horton, N C.]]
[[Category: Chang G]]
[[Category: Kercher, M A.]]
[[Category: Horton NC]]
[[Category: Lewis, M.]]
[[Category: Kercher MA]]
[[Category: Lu, P.]]
[[Category: Lewis M]]
[[Category: Pace, H C.]]
[[Category: Lu P]]
[[Category: Dna-binding]]
[[Category: Pace HC]]
[[Category: Repressor]]
[[Category: Transcription regulation]]
[[Category: Transcription-dna complex]]

Latest revision as of 10:31, 14 February 2024

LACTOSE OPERON REPRESSOR BOUND TO 21-BASE PAIR SYMMETRIC OPERATOR DNA, ALPHA CARBONS ONLYLACTOSE OPERON REPRESSOR BOUND TO 21-BASE PAIR SYMMETRIC OPERATOR DNA, ALPHA CARBONS ONLY

Structural highlights

1lbg is a 8 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 4.8Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LACI_ECOLI Repressor of the lactose operon. Binds allolactose as an inducer.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1lbg, resolution 4.80Å

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