1l3a: Difference between revisions

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==Structure of the plant transcriptional regulator PBF-2==
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<StructureSection load='1l3a' size='340' side='right'caption='[[1l3a]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1l3a]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Solanum_tuberosum Solanum tuberosum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L3A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L3A FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l3a OCA], [https://pdbe.org/1l3a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l3a RCSB], [https://www.ebi.ac.uk/pdbsum/1l3a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l3a ProSAT]</span></td></tr>
{{STRUCTURE_1l3a|  PDB=1l3a  |  SCENE=  }}
</table>
 
== Function ==
===Structure of the plant transcriptional regulator PBF-2===
[https://www.uniprot.org/uniprot/WHY1_SOLTU WHY1_SOLTU] Single-stranded DNA-binding protein that acts as a transcriptional activator of the pathogenesis-related gene PR-10a. Upon elicitation, binds a 30bp promoter sequence known as elicitor element response (ERE) and is required for PR-10a expression.<ref>PMID:10948264</ref> <ref>PMID:12080340</ref> <ref>PMID:14960277</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1l3a ConSurf].
1L3A is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Solanum_tuberosum Solanum tuberosum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L3A OCA].  
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== References ==
==Reference==
<references/>
<ref group="xtra">PMID:12080340</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Solanum tuberosum]]
[[Category: Solanum tuberosum]]
[[Category: Allard, J.]]
[[Category: Allard J]]
[[Category: Brisson, N.]]
[[Category: Brisson N]]
[[Category: Desveaux, D.]]
[[Category: Desveaux D]]
[[Category: Sygusch, J.]]
[[Category: Sygusch J]]
[[Category: Cyclic c4 symmetry]]
[[Category: Pbf-2]]
[[Category: Plant]]
[[Category: Single strand dna binding protein]]
[[Category: Transcriptionnal activator]]
[[Category: Whirly]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 07:54:35 2009''

Latest revision as of 10:29, 14 February 2024

Structure of the plant transcriptional regulator PBF-2Structure of the plant transcriptional regulator PBF-2

Structural highlights

1l3a is a 4 chain structure with sequence from Solanum tuberosum. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

WHY1_SOLTU Single-stranded DNA-binding protein that acts as a transcriptional activator of the pathogenesis-related gene PR-10a. Upon elicitation, binds a 30bp promoter sequence known as elicitor element response (ERE) and is required for PR-10a expression.[1] [2] [3]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Desveaux D, Despres C, Joyeux A, Subramaniam R, Brisson N. PBF-2 is a novel single-stranded DNA binding factor implicated in PR-10a gene activation in potato. Plant Cell. 2000 Aug;12(8):1477-89. PMID:10948264
  2. Desveaux D, Allard J, Brisson N, Sygusch J. A new family of plant transcription factors displays a novel ssDNA-binding surface. Nat Struct Biol. 2002 Jul;9(7):512-7. PMID:12080340 doi:10.1038/nsb814
  3. Desveaux D, Subramaniam R, Despres C, Mess JN, Levesque C, Fobert PR, Dangl JL, Brisson N. A "Whirly" transcription factor is required for salicylic acid-dependent disease resistance in Arabidopsis. Dev Cell. 2004 Feb;6(2):229-40. PMID:14960277

1l3a, resolution 2.30Å

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