1l3a: Difference between revisions

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[[Image:1l3a.png|left|200px]]


{{STRUCTURE_1l3a|  PDB=1l3a  |  SCENE=  }}
==Structure of the plant transcriptional regulator PBF-2==
 
<StructureSection load='1l3a' size='340' side='right'caption='[[1l3a]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
===Structure of the plant transcriptional regulator PBF-2===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1l3a]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Solanum_tuberosum Solanum tuberosum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L3A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L3A FirstGlance]. <br>
{{ABSTRACT_PUBMED_12080340}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l3a OCA], [https://pdbe.org/1l3a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l3a RCSB], [https://www.ebi.ac.uk/pdbsum/1l3a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l3a ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1l3a]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Solanum_tuberosum Solanum tuberosum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L3A OCA].  
== Function ==
 
[https://www.uniprot.org/uniprot/WHY1_SOLTU WHY1_SOLTU] Single-stranded DNA-binding protein that acts as a transcriptional activator of the pathogenesis-related gene PR-10a. Upon elicitation, binds a 30bp promoter sequence known as elicitor element response (ERE) and is required for PR-10a expression.<ref>PMID:10948264</ref> <ref>PMID:12080340</ref> <ref>PMID:14960277</ref>
==Reference==
== Evolutionary Conservation ==
<ref group="xtra">PMID:012080340</ref><ref group="xtra">PMID:020551348</ref><references group="xtra"/>
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l3/1l3a_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1l3a ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Solanum tuberosum]]
[[Category: Solanum tuberosum]]
[[Category: Allard, J.]]
[[Category: Allard J]]
[[Category: Brisson, N.]]
[[Category: Brisson N]]
[[Category: Desveaux, D.]]
[[Category: Desveaux D]]
[[Category: Sygusch, J.]]
[[Category: Sygusch J]]
[[Category: Cyclic c4 symmetry]]
[[Category: Dna binding protein]]
[[Category: Pbf-2]]
[[Category: Plant]]
[[Category: Single strand dna binding protein]]
[[Category: Transcriptionnal activator]]
[[Category: Whirly]]

Latest revision as of 10:29, 14 February 2024

Structure of the plant transcriptional regulator PBF-2Structure of the plant transcriptional regulator PBF-2

Structural highlights

1l3a is a 4 chain structure with sequence from Solanum tuberosum. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

WHY1_SOLTU Single-stranded DNA-binding protein that acts as a transcriptional activator of the pathogenesis-related gene PR-10a. Upon elicitation, binds a 30bp promoter sequence known as elicitor element response (ERE) and is required for PR-10a expression.[1] [2] [3]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Desveaux D, Despres C, Joyeux A, Subramaniam R, Brisson N. PBF-2 is a novel single-stranded DNA binding factor implicated in PR-10a gene activation in potato. Plant Cell. 2000 Aug;12(8):1477-89. PMID:10948264
  2. ↑ Desveaux D, Allard J, Brisson N, Sygusch J. A new family of plant transcription factors displays a novel ssDNA-binding surface. Nat Struct Biol. 2002 Jul;9(7):512-7. PMID:12080340 doi:10.1038/nsb814
  3. ↑ Desveaux D, Subramaniam R, Despres C, Mess JN, Levesque C, Fobert PR, Dangl JL, Brisson N. A "Whirly" transcription factor is required for salicylic acid-dependent disease resistance in Arabidopsis. Dev Cell. 2004 Feb;6(2):229-40. PMID:14960277

1l3a, resolution 2.30Å

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