1kuv: Difference between revisions

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-{{Seed}}
-[[Image:1kuv.png|left|200px]]
-<!--
+==X-ray Crystallographic Studies of Serotonin N-acetyltransferase Catalysis and Inhibition==
-The line below this paragraph, containing "STRUCTURE_1kuv", creates the "Structure Box" on the page.
+<StructureSection load='1kuv' size='340' side='right'caption='[[1kuv]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1kuv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ovis_aries Ovis aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KUV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KUV FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA5:COA-S-ACETYL+5-BROMOTRYPTAMINE'>CA5</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-{{STRUCTURE_1kuv|  PDB=1kuv  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kuv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kuv OCA], [https://pdbe.org/1kuv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kuv RCSB], [https://www.ebi.ac.uk/pdbsum/1kuv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kuv ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SNAT_SHEEP SNAT_SHEEP] Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin.<ref>PMID:15644438</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ku/1kuv_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kuv ConSurf].
+<div style="clear:both"></div>
-===X-ray Crystallographic Studies of Serotonin N-acetyltransferase Catalysis and Inhibition===
+==See Also==
+*[[Serotonin N-acetyltransferase|Serotonin N-acetyltransferase]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_11902838}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 11902838 is the PubMed ID number.
+</StructureSection>
--->
+[[Category: Large Structures]]
-{{ABSTRACT_PUBMED_11902838}}
-==About this Structure==
-KUV is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Ovis_aries Ovis aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KUV OCA].
-==Reference==
-<ref group="xtra">PMID:11902838</ref><references group="xtra"/>
-[[Category: Aralkylamine N-acetyltransferase]]
 [[Category: Ovis aries]]
-[[Category: Angelis, J De.]]
+[[Category: Burley SK]]
-[[Category: Burley, S K.]]
+[[Category: Cole PA]]
-[[Category: Cole, P A.]]
+[[Category: De Angelis J]]
-[[Category: Khalil, E M.]]
+[[Category: Khalil EM]]
-[[Category: Wolf, E.]]
+[[Category: Wolf E]]
-[[Category: Alternate conformation]]
-[[Category: Bisubstrate analog]]
-[[Category: Enzyme-inhibitor complex]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 07:43:39 2009''