1kqc: Difference between revisions

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-{{Seed}}
-[[Image:1kqc.png|left|200px]]
-<!--
+==Structure of Nitroreductase from E. cloacae Complex with Inhibitor Acetate==
-The line below this paragraph, containing "STRUCTURE_1kqc", creates the "Structure Box" on the page.
+<StructureSection load='1kqc' size='340' side='right'caption='[[1kqc]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1kqc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacter_cloacae Enterobacter cloacae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KQC FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
-{{STRUCTURE_1kqc|  PDB=1kqc  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kqc OCA], [https://pdbe.org/1kqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kqc RCSB], [https://www.ebi.ac.uk/pdbsum/1kqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kqc ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/NFSB_ENTCL NFSB_ENTCL] Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kq/1kqc_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kqc ConSurf].
+<div style="clear:both"></div>
-===Structure of Nitroreductase from E. cloacae Complex with Inhibitor Acetate===
+==See Also==
+*[[Nitroreductase 3D structures|Nitroreductase 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_11805110}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 11805110 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_11805110}}
-==About this Structure==
-KQC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacter_cloacae Enterobacter cloacae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KQC OCA].
-==Reference==
-Structures of nitroreductase in three states: effects of inhibitor binding and reduction., Haynes CA, Koder RL, Miller AF, Rodgers DW, J Biol Chem. 2002 Mar 29;277(13):11513-20. Epub 2002 Jan 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11805110 11805110]
 [[Category: Enterobacter cloacae]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Haynes, C A.]]
+[[Category: Haynes CA]]
-[[Category: Koder, R L.]]
+[[Category: Koder RL]]
-[[Category: Miller, A F.]]
+[[Category: Miller AF]]
-[[Category: Rodgers, D W.]]
+[[Category: Rodgers DW]]
-[[Category: Acetate]]
-[[Category: Flavin]]
-[[Category: Nitroreductase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  2 10:45:43 2008''