1kpl: Difference between revisions

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-{{Seed}}
-[[Image:1kpl.png|left|200px]]
-<!--
+==Crystal Structure of the ClC Chloride Channel from S. typhimurium==
-The line below this paragraph, containing "STRUCTURE_1kpl", creates the "Structure Box" on the page.
+<StructureSection load='1kpl' size='340' side='right'caption='[[1kpl]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1kpl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KPL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KPL FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MYS:PENTADECANE'>MYS</scene>, <scene name='pdbligand=OCT:N-OCTANE'>OCT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-{{STRUCTURE_1kpl|  PDB=1kpl  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kpl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kpl OCA], [https://pdbe.org/1kpl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kpl RCSB], [https://www.ebi.ac.uk/pdbsum/1kpl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kpl ProSAT]</span></td></tr>
+</table>
-===Crystal Structure of the ClC Chloride Channel from S. typhimurium===
+== Function ==
+[https://www.uniprot.org/uniprot/CLCA_SALTY CLCA_SALTY] Proton-coupled chloride transporter. Functions as antiport system and exchanges two chloride ions for 1 proton. Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.<ref>PMID:11796999</ref>
+== Evolutionary Conservation ==
-<!--
+[[Image:Consurf_key_small.gif|200px|right]]
-The line below this paragraph, {{ABSTRACT_PUBMED_11796999}}, adds the Publication Abstract to the page
+Check<jmol>
-(as it appears on PubMed at http://www.pubmed.gov), where 11796999 is the PubMed ID number.
+  <jmolCheckbox>
--->
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kp/1kpl_consurf.spt"</scriptWhenChecked>
-{{ABSTRACT_PUBMED_11796999}}
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
-==About this Structure==
+  </jmolCheckbox>
-KPL is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KPL OCA].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kpl ConSurf].
+<div style="clear:both"></div>
-==Reference==
+== References ==
-<ref group="xtra">PMID:11796999</ref><references group="xtra"/>
+<references/>
-[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
+__TOC__
-[[Category: Cadene, M.]]
+</StructureSection>
-[[Category: Campbell, E B.]]
+[[Category: Large Structures]]
-[[Category: Chait, B T.]]
+[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
-[[Category: Dutzler, R.]]
+[[Category: Cadene M]]
-[[Category: MacKinnon, R.]]
+[[Category: Campbell EB]]
-[[Category: Helical membrane protein]]
+[[Category: Chait BT]]
-[[Category: Homodimer]]
+[[Category: Dutzler R]]
-[[Category: Ion channel]]
+[[Category: MacKinnon R]]
-[[Category: Membrane protein]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 22 09:07:44 2010''