3mc5: Difference between revisions

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-[[Image:3mc5.jpg|left|200px]]
-<!--
+==Human Aldose Reductase mutant T113V in complex with IDD393 crystallized in spacegroup P1==
-The line below this paragraph, containing "STRUCTURE_3mc5", creates the "Structure Box" on the page.
+<StructureSection load='3mc5' size='340' side='right'caption='[[3mc5]], [[Resolution|resolution]] 1.14&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3mc5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MC5 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.14&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=393:(5-CHLORO-2-{[(3-NITROBENZYL)AMINO]CARBONYL}PHENOXY)ACETIC+ACID'>393</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
-{{STRUCTURE_3mc5|  PDB=3mc5  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mc5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mc5 OCA], [https://pdbe.org/3mc5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mc5 RCSB], [https://www.ebi.ac.uk/pdbsum/3mc5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mc5 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
-===Human Aldose Reductase mutant T113V in complex with IDD393 crystallized in spacegroup P1===
+==See Also==
+*[[Aldose reductase 3D structures|Aldose reductase 3D structures]]
+__TOC__
-==About this Structure==
+</StructureSection>
-[[3mc5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC5 OCA].
-[[Category: Aldehyde reductase]]
 [[Category: Homo sapiens]]
-[[Category: Heine, A.]]
+[[Category: Large Structures]]
-[[Category: Klebe, G.]]
+[[Category: Heine A]]
-[[Category: Koch, C.]]
+[[Category: Klebe G]]
+[[Category: Koch C]]