3m5l: Difference between revisions

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-{{STRUCTURE_3m5l|  PDB=3m5l  |  SCENE=  }}
-===Crystal structure of HCV NS3/4A protease in complex with ITMN-191===
-{{ABSTRACT_PUBMED_21084633}}
-==About this Structure==
+==Crystal structure of HCV NS3/4A protease in complex with ITMN-191==
-[[3m5l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1a Hepatitis c virus subtype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M5L OCA].
+<StructureSection load='3m5l' size='340' side='right'caption='[[3m5l]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3m5l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_C_virus_genotype_1a Hepatitis C virus genotype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M5L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3M5L FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TSV:(2R,6S,12Z,13AS,14AR,16AS)-6-[(TERT-BUTOXYCARBONYL)AMINO]-14A-[(CYCLOPROPYLSULFONYL)CARBAMOYL]-5,16-DIOXO-1,2,3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-HEXADECAHYDROCYCLOPROPA[E]PYRROLO[1,2-A][1,4]DIAZACYCLOPENTADECIN-2-YL+4-FLUORO-2H-ISOINDOLE-2-CARBOXYLATE'>TSV</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3m5l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m5l OCA], [https://pdbe.org/3m5l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3m5l RCSB], [https://www.ebi.ac.uk/pdbsum/3m5l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3m5l ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/A8DG50_9HEPC A8DG50_9HEPC]
-==Reference==
+==See Also==
-<ref group="xtra">PMID:021084633</ref><references group="xtra"/><references/>
+*[[Virus protease 3D structures|Virus protease 3D structures]]
-[[Category: Hepacivirin]]
+__TOC__
-[[Category: Hepatitis c virus subtype 1a]]
+</StructureSection>
-[[Category: Romano, K P.]]
+[[Category: Hepatitis C virus genotype 1a]]
-[[Category: Schiffer, C A.]]
+[[Category: Large Structures]]
-[[Category: Chimera protein]]
+[[Category: Romano KP]]
-[[Category: Drug resistance]]
+[[Category: Schiffer CA]]
-[[Category: Fusion protein]]
-[[Category: Hcv]]
-[[Category: Hepatitis c virus]]
-[[Category: Hydrolase-hydrolase inhibitor complex]]
-[[Category: Ns3]]
-[[Category: Protease]]
-[[Category: Serine protease]]