3m5l: Difference between revisions

No edit summary
No edit summary
 
(5 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Seed}}
[[Image:3m5l.png|left|200px]]


<!--
==Crystal structure of HCV NS3/4A protease in complex with ITMN-191==
The line below this paragraph, containing "STRUCTURE_3m5l", creates the "Structure Box" on the page.
<StructureSection load='3m5l' size='340' side='right'caption='[[3m5l]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3m5l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_C_virus_genotype_1a Hepatitis C virus genotype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M5L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3M5L FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TSV:(2R,6S,12Z,13AS,14AR,16AS)-6-[(TERT-BUTOXYCARBONYL)AMINO]-14A-[(CYCLOPROPYLSULFONYL)CARBAMOYL]-5,16-DIOXO-1,2,3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-HEXADECAHYDROCYCLOPROPA[E]PYRROLO[1,2-A][1,4]DIAZACYCLOPENTADECIN-2-YL+4-FLUORO-2H-ISOINDOLE-2-CARBOXYLATE'>TSV</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_3m5l|  PDB=3m5l  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3m5l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m5l OCA], [https://pdbe.org/3m5l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3m5l RCSB], [https://www.ebi.ac.uk/pdbsum/3m5l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3m5l ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A8DG50_9HEPC A8DG50_9HEPC]


===Crystal structure of HCV NS3/4A protease in complex with ITMN-191===
==See Also==
 
*[[Virus protease 3D structures|Virus protease 3D structures]]
 
__TOC__
<!--
</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_21084633}}, adds the Publication Abstract to the page
[[Category: Hepatitis C virus genotype 1a]]
(as it appears on PubMed at http://www.pubmed.gov), where 21084633 is the PubMed ID number.
[[Category: Large Structures]]
-->
[[Category: Romano KP]]
{{ABSTRACT_PUBMED_21084633}}
[[Category: Schiffer CA]]
 
==About this Structure==
3M5L is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1a Hepatitis c virus subtype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M5L OCA].
 
==Reference==
<ref group="xtra">PMID:21084633</ref><references group="xtra"/>
[[Category: Hepacivirin]]
[[Category: Hepatitis c virus subtype 1a]]
[[Category: Romano, K P.]]
[[Category: Schiffer, C A.]]
[[Category: Chimera protein]]
[[Category: Drug resistance]]
[[Category: Fusion protein]]
[[Category: Hcv]]
[[Category: Hepatitis c virus]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Ns3]]
[[Category: Protease]]
[[Category: Serine protease]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 22 09:25:14 2010''

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA