3m4h: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
m Protected "3m4h" [edit=sysop:move=sysop]
No edit summary
 
(6 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:3m4h.png|left|200px]]


<!--
==Human Aldose Reductase mutant T113V complexed with IDD388==
The line below this paragraph, containing "STRUCTURE_3m4h", creates the "Structure Box" on the page.
<StructureSection load='3m4h' size='340' side='right'caption='[[3m4h]], [[Resolution|resolution]] 0.94&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3m4h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M4H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3M4H FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.94&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=388:(2-{[(4-BROMO-2-FLUOROBENZYL)AMINO]CARBONYL}-5-CHLOROPHENOXY)ACETIC+ACID'>388</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
{{STRUCTURE_3m4h|  PDB=3m4h  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3m4h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m4h OCA], [https://pdbe.org/3m4h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3m4h RCSB], [https://www.ebi.ac.uk/pdbsum/3m4h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3m4h ProSAT]</span></td></tr>
 
</table>
===Human Aldose Reductase mutant T113V complexed with IDD388===
== Function ==
 
[https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
 
<!--
The line below this paragraph, {{ABSTRACT_PUBMED_21185307}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 21185307 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_21185307}}
 
==About this Structure==
[[3m4h]] is a 1 chain structure of [[Aldose Reductase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M4H OCA].  


==See Also==
==See Also==
*[[Aldose Reductase]]
*[[Aldose reductase 3D structures|Aldose reductase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:021185307</ref><references group="xtra"/>
[[Category: Aldehyde reductase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Heine, A.]]
[[Category: Large Structures]]
[[Category: Klebe, G.]]
[[Category: Heine A]]
[[Category: Koch, C.]]
[[Category: Klebe G]]
[[Category: Nadp]]
[[Category: Koch C]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
[[Category: Phosphoprotein]]
[[Category: T113v mutant]]

Latest revision as of 11:47, 7 February 2024

Human Aldose Reductase mutant T113V complexed with IDD388Human Aldose Reductase mutant T113V complexed with IDD388

Structural highlights

3m4h is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 0.94Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ALDR_HUMAN Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.

See Also

3m4h, resolution 0.94Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=3m4h&oldid=4047948"