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==Cryo-EM structure of GTPgammaS-microtubule co-polymerized with EB3 (merged dataset with and without kinesin bound)== | |||
<SX load='3jak' size='340' side='right' viewer='molstar' caption='[[3jak]], [[Resolution|resolution]] 3.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3jak]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JAK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JAK FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSP:5-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE'>GSP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jak OCA], [https://pdbe.org/3jak PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jak RCSB], [https://www.ebi.ac.uk/pdbsum/3jak PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jak ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TBA1B_PIG TBA1B_PIG] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | |||
==See Also== | |||
*[[End-binding protein|End-binding protein]] | |||
*[[Microtubule-associated protein 3D structures|Microtubule-associated protein 3D structures]] | |||
[[Category: | __TOC__ | ||
[[Category: Nogales | </SX> | ||
[[Category: Zhang | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | |||
[[Category: Sus scrofa]] | |||
[[Category: Nogales E]] | |||
[[Category: Zhang R]] | |||
Latest revision as of 11:42, 7 February 2024
Cryo-EM structure of GTPgammaS-microtubule co-polymerized with EB3 (merged dataset with and without kinesin bound)Cryo-EM structure of GTPgammaS-microtubule co-polymerized with EB3 (merged dataset with and without kinesin bound)
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