8aht: Difference between revisions

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'''Unreleased structure'''


The entry 8aht is ON HOLD
==Crystal structure of Plasmodium falciparum Ca2+/Calmodulin in complex with melittin==
 
<StructureSection load='8aht' size='340' side='right'caption='[[8aht]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
Authors: Durvanger, Z., Harmat, V.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8aht]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Apis_mellifera Apis mellifera] and [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8AHT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8AHT FirstGlance]. <br>
Description: Crystal structure of Plasmodium falciparum Ca2+/Calmodulin in complex with melittin
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
[[Category: Durvanger, Z]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8aht FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8aht OCA], [https://pdbe.org/8aht PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8aht RCSB], [https://www.ebi.ac.uk/pdbsum/8aht PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8aht ProSAT]</span></td></tr>
[[Category: Harmat, V]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/CALM_PLAF7 CALM_PLAF7] Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+) (PubMed:32821880). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (PubMed:32821880).<ref>PMID:32821880</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Apis mellifera]]
[[Category: Large Structures]]
[[Category: Plasmodium falciparum]]
[[Category: Durvanger Z]]
[[Category: Harmat V]]

Latest revision as of 11:11, 7 February 2024

Crystal structure of Plasmodium falciparum Ca2+/Calmodulin in complex with melittinCrystal structure of Plasmodium falciparum Ca2+/Calmodulin in complex with melittin

Structural highlights

8aht is a 8 chain structure with sequence from Apis mellifera and Plasmodium falciparum. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CALM_PLAF7 Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+) (PubMed:32821880). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (PubMed:32821880).[1]

References

  1. ↑ Juhász T, Kardos J, Dürvanger Z, Harmat V, Liliom K. Comparison of ligand binding and conformational stability of human calmodulin with its homolog from the malaria parasite Plasmodium falciparum. FASEB Bioadv. 2020 Aug 9;2(8):489-505. PMID:32821880 doi:10.1096/fba.2020-00013

8aht, resolution 2.20Å

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