8a1p: Difference between revisions
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==HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor BI-D== | |||
<StructureSection load='8a1p' size='340' side='right'caption='[[8a1p]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8a1p]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8A1P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8A1P FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LF0:(2S)-TERT-BUTOXY[4-(3,4-DIHYDRO-2H-CHROMEN-6-YL)-2-METHYLQUINOLIN-3-YL]ETHANOIC+ACID'>LF0</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8a1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8a1p OCA], [https://pdbe.org/8a1p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8a1p RCSB], [https://www.ebi.ac.uk/pdbsum/8a1p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8a1p ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/Q76353_9HIV1 Q76353_9HIV1] | |||
==See Also== | |||
*[[Retroviral integrase 3D structures|Retroviral integrase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Human immunodeficiency virus 1]] | |||
[[Category: Large Structures]] | |||
[[Category: Cherepanov P]] | |||
[[Category: Cook NJ]] | |||
[[Category: Pye VE]] | |||
[[Category: Singer MR]] |