2jcp: Difference between revisions

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-[[Image:2jcp.gif|left|200px]]
- {{Structure
+==The hyaluronan binding domain of murine CD44==
-|PDB= 2jcp |SIZE=350|CAPTION= <scene name='initialview01'>2jcp</scene>, resolution 1.30&Aring;
+<StructureSection load='2jcp' size='340' side='right'caption='[[2jcp]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND=
+<table><tr><td colspan='2'>[[2jcp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JCP FirstGlance]. <br>
-|ACTIVITY=
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
-|GENE=
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jcp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jcp OCA], [https://pdbe.org/2jcp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jcp RCSB], [https://www.ebi.ac.uk/pdbsum/2jcp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jcp ProSAT]</span></td></tr>
-}}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CD44_MOUSE CD44_MOUSE] Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jc/2jcp_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jcp ConSurf].
+<div style="clear:both"></div>
-'''THE HYALURONAN BINDING DOMAIN OF MURINE CD44'''
+==See Also==
+*[[CD44|CD44]]
+__TOC__
-==About this Structure==
+</StructureSection>
-JCP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCP OCA].
+[[Category: Large Structures]]
 [[Category: Mus musculus]]
-[[Category: Single protein]]
+[[Category: Banerji S]]
-[[Category: Banerji, S.]]
+[[Category: Campbell ID]]
-[[Category: Campbell, I D.]]
+[[Category: Day AJ]]
-[[Category: Day, A J.]]
+[[Category: Jackson DG]]
-[[Category: Jackson, D G.]]
+[[Category: Mahoney DJ]]
-[[Category: Mahoney, D J.]]
+[[Category: Noble MEM]]
-[[Category: Noble, M E.M.]]
+[[Category: Wright AJ]]
-[[Category: Wright, A J.]]
-[[Category: alternative splicing]]
-[[Category: antigen]]
-[[Category: blood group antigen]]
-[[Category: c-type lectin]]
-[[Category: cell adhesion]]
-[[Category: extracellular matrix]]
-[[Category: glycoprotein]]
-[[Category: hyauronan]]
-[[Category: lectin]]
-[[Category: link-domain]]
-[[Category: membrane]]
-[[Category: phosphorylation]]
-[[Category: polymorphism]]
-[[Category: proteoglycan]]
-[[Category: pyrrolidone carboxylic acid]]
-[[Category: receptor]]
-[[Category: sugar- binding]]
-[[Category: sulfation]]
-[[Category: transmembrane]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:40:10 2008''