1kag: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
No edit summary
No edit summary
 
(13 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:1kag.gif|left|200px]]


{{Structure
==Crystal Structure of the Escherichia coli Shikimate Kinase I (AroK)==
|PDB= 1kag |SIZE=350|CAPTION= <scene name='initialview01'>1kag</scene>, resolution 2.05&Aring;
<StructureSection load='1kag' size='340' side='right'caption='[[1kag]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1kag]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KAG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KAG FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Shikimate_kinase Shikimate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.71 2.7.1.71] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
|GENE= AROK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kag FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kag OCA], [https://pdbe.org/1kag PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kag RCSB], [https://www.ebi.ac.uk/pdbsum/1kag PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kag ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1kag TOPSAN]</span></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00464 SK], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK00131 aroK]</span>
</table>
|RELATEDENTRY=[[1shk|1SHK]]
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kag FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kag OCA], [http://www.ebi.ac.uk/pdbsum/1kag PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1kag RCSB]</span>
[https://www.uniprot.org/uniprot/AROK_ECOLI AROK_ECOLI] Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.<ref>PMID:1309529</ref>
}}
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ka/1kag_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kag ConSurf].
<div style="clear:both"></div>


'''Crystal Structure of the Escherichia coli Shikimate Kinase I (AroK)'''
==See Also==
 
*[[Shikimate kinase 3D structures|Shikimate kinase 3D structures]]
 
== References ==
==About this Structure==
<references/>
1KAG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KAG OCA].
__TOC__
 
</StructureSection>
==Reference==
Crystal structure of the Escherichia coli shikimate kinase I (AroK) that confers sensitivity to mecillinam., Romanowski MJ, Burley SK, Proteins. 2002 Jun 1;47(4):558-62. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12001235 12001235]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Shikimate kinase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Burley SK]]
[[Category: Burley, S K.]]
[[Category: Romanowski MJ]]
[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
[[Category: Romanowski, M J.]]
[[Category: new york structural genomix research consortium]]
[[Category: nysgxrc]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomic]]
[[Category: transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:45:42 2008''

Latest revision as of 10:45, 7 February 2024

Crystal Structure of the Escherichia coli Shikimate Kinase I (AroK)Crystal Structure of the Escherichia coli Shikimate Kinase I (AroK)

Structural highlights

1kag is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.05Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

AROK_ECOLI Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Lobner-Olesen A, Marinus MG. Identification of the gene (aroK) encoding shikimic acid kinase I of Escherichia coli. J Bacteriol. 1992 Jan;174(2):525-9. PMID:1309529

1kag, resolution 2.05Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=1kag&oldid=4045751"