1jwn: Difference between revisions

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[[Image:1jwn.png|left|200px]]


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==Crystal Structure of Scapharca inaequivalvis HbI, I114F Mutant Ligated to Carbon Monoxide.==
The line below this paragraph, containing "STRUCTURE_1jwn", creates the "Structure Box" on the page.
<StructureSection load='1jwn' size='340' side='right'caption='[[1jwn]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1jwn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Anadara_inaequivalvis Anadara inaequivalvis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JWN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JWN FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMO:CARBON+MONOXIDE'>CMO</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
{{STRUCTURE_1jwn|  PDB=1jwn |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jwn OCA], [https://pdbe.org/1jwn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jwn RCSB], [https://www.ebi.ac.uk/pdbsum/1jwn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jwn ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GLB1_ANAIN GLB1_ANAIN]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jw/1jwn_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jwn ConSurf].
<div style="clear:both"></div>


===Crystal Structure of Scapharca inaequivalvis HbI, I114F Mutant Ligated to Carbon Monoxide.===
==See Also==
 
*[[Hemoglobin 3D structures|Hemoglobin 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_11732898}}, adds the Publication Abstract to the page
[[Category: Anadara inaequivalvis]]
(as it appears on PubMed at http://www.pubmed.gov), where 11732898 is the PubMed ID number.
[[Category: Large Structures]]
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[[Category: Cushing L]]
{{ABSTRACT_PUBMED_11732898}}
[[Category: Gibson QH]]
 
[[Category: Knapp JE]]
==About this Structure==
[[Category: Royer Jr WE]]
1JWN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Scapharca_inaequivalvis Scapharca inaequivalvis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JWN OCA].
 
==Reference==
Restricting the ligand-linked heme movement in Scapharca dimeric hemoglobin reveals tight coupling between distal and proximal contributions to cooperativity., Knapp JE, Gibson QH, Cushing L, Royer WE Jr, Biochemistry. 2001 Dec 11;40(49):14795-805. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11732898 11732898]
[[Category: Scapharca inaequivalvis]]
[[Category: Single protein]]
[[Category: Cushing, L.]]
[[Category: Gibson, Q H.]]
[[Category: Jr., W E.Royer.]]
[[Category: Knapp, J E.]]
[[Category: Allostery]]
[[Category: Cooperativity]]
[[Category: Heme protein]]
[[Category: Invertebrate hemoglobin]]
[[Category: Oxygen-binding protein]]
 
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