1jt0: Difference between revisions

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OCA

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-{{Seed}}
-[[Image:1jt0.png|left|200px]]
-<!--
+==Crystal structure of a cooperative QacR-DNA complex==
-The line below this paragraph, containing "STRUCTURE_1jt0", creates the "Structure Box" on the page.
+<StructureSection load='1jt0' size='340' side='right'caption='[[1jt0]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1jt0]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JT0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JT0 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-{{STRUCTURE_1jt0|  PDB=1jt0  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jt0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jt0 OCA], [https://pdbe.org/1jt0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jt0 RCSB], [https://www.ebi.ac.uk/pdbsum/1jt0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jt0 ProSAT]</span></td></tr>
+</table>
-===Crystal structure of a cooperative QacR-DNA complex===
+== Function ==
+[https://www.uniprot.org/uniprot/QACR_STAAU QACR_STAAU] Transcriptional repressor of qacA. Binds to IR1, an unusually long 28 bp operator, which is located downstream from the qacA promoter and overlaps its transcription start site. QacR is induced from its IR1 site by binding to one of many structurally dissimilar cationic lipophilic compounds, which are also substrates of QacA.
+== Evolutionary Conservation ==
-<!--
+[[Image:Consurf_key_small.gif|200px|right]]
-The line below this paragraph, {{ABSTRACT_PUBMED_11867549}}, adds the Publication Abstract to the page
+Check<jmol>
-(as it appears on PubMed at http://www.pubmed.gov), where 11867549 is the PubMed ID number.
+  <jmolCheckbox>
--->
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jt/1jt0_consurf.spt"</scriptWhenChecked>
-{{ABSTRACT_PUBMED_11867549}}
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
-==About this Structure==
+  </jmolCheckbox>
-JT0 is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JT0 OCA].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jt0 ConSurf].
+<div style="clear:both"></div>
-==Reference==
+__TOC__
-<ref group="xtra">PMID:11867549</ref><references group="xtra"/>
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Staphylococcus aureus]]
-[[Category: Brennan, R G.]]
+[[Category: Brennan RG]]
-[[Category: Brown, M H.]]
+[[Category: Brown MH]]
-[[Category: Grkovic, S.]]
+[[Category: Grkovic S]]
-[[Category: Miller, M C.]]
+[[Category: Miller MC]]
-[[Category: Schumacher, M A.]]
+[[Category: Schumacher MA]]
-[[Category: Skurray, R A.]]
+[[Category: Skurray RA]]
-[[Category: Cooperative dna binding]]
-[[Category: Dimer of dimer]]
-[[Category: Multidrug binding protein]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:31:24 2009''