1jot: Difference between revisions

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[[Image:1jot.png|left|200px]]


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==STRUCTURE OF THE LECTIN MPA COMPLEXED WITH T-ANTIGEN DISACCHARIDE==
The line below this paragraph, containing "STRUCTURE_1jot", creates the "Structure Box" on the page.
<StructureSection load='1jot' size='340' side='right'caption='[[1jot]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1jot]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Maclura_pomifera Maclura pomifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JOT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JOT FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=PRD_900084:Thomsen-Friedenreich+antigen'>PRD_900084</scene></td></tr>
{{STRUCTURE_1jot| PDB=1jot |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jot OCA], [https://pdbe.org/1jot PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jot RCSB], [https://www.ebi.ac.uk/pdbsum/1jot PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jot ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LECA_MACPO LECA_MACPO] D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jo/1jot_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jot ConSurf].
<div style="clear:both"></div>


===STRUCTURE OF THE LECTIN MPA COMPLEXED WITH T-ANTIGEN DISACCHARIDE===
==See Also==
 
*[[Agglutinin 3D structures|Agglutinin 3D structures]]
 
__TOC__
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_9497359}}
 
==About this Structure==
1JOT is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Maclura_pomifera Maclura pomifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JOT OCA].
 
==Reference==
Structure of the complex of Maclura pomifera agglutinin and the T-antigen disaccharide, Galbeta1,3GalNAc., Lee X, Thompson A, Zhang Z, Ton-that H, Biesterfeldt J, Ogata C, Xu L, Johnston RA, Young NM, J Biol Chem. 1998 Mar 13;273(11):6312-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9497359 9497359]
[[Category: Maclura pomifera]]
[[Category: Maclura pomifera]]
[[Category: Protein complex]]
[[Category: Biesterfeldt J]]
[[Category: Biesterfeldt, J.]]
[[Category: Hoa T-T]]
[[Category: Hoa, T T.]]
[[Category: Johnston RAZ]]
[[Category: Johnston, R A.Z.]]
[[Category: Lee X]]
[[Category: Lee, X.]]
[[Category: Ogata C]]
[[Category: Ogata, C.]]
[[Category: Thompson A]]
[[Category: Thompson, A.]]
[[Category: Xu L]]
[[Category: Xu, L.]]
[[Category: Young NM]]
[[Category: Young, N M.]]
[[Category: Zhang Z]]
[[Category: Zhang, Z.]]
[[Category: Beta prism]]
[[Category: Lectin]]
[[Category: Maclura pomifera]]
[[Category: T-antigen]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 20:34:17 2008''

Latest revision as of 10:41, 7 February 2024

STRUCTURE OF THE LECTIN MPA COMPLEXED WITH T-ANTIGEN DISACCHARIDESTRUCTURE OF THE LECTIN MPA COMPLEXED WITH T-ANTIGEN DISACCHARIDE

Structural highlights

1jot is a 2 chain structure with sequence from Maclura pomifera. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LECA_MACPO D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1jot, resolution 2.20Å

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