1jnm: Difference between revisions

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-[[Image:1jnm.png|left|200px]]
-{{STRUCTURE_1jnm|  PDB=1jnm  |  SCENE=  }}
+==Crystal Structure of the Jun/CRE Complex==
+<StructureSection load='1jnm' size='340' side='right'caption='[[1jnm]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-===Crystal Structure of the Jun/CRE Complex===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1jnm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JNM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JNM FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jnm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jnm OCA], [https://pdbe.org/1jnm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jnm RCSB], [https://www.ebi.ac.uk/pdbsum/1jnm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jnm ProSAT]</span></td></tr>
-[[1jnm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JNM OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/JUN_HUMAN JUN_HUMAN] Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.<ref>PMID:10995748</ref> <ref>PMID:17210646</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jn/1jnm_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jnm ConSurf].
+<div style="clear:both"></div>
 ==See Also==
 *[[C-JUN|C-JUN]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Kim, Y.]]
+[[Category: Large Structures]]
-[[Category: Podust, L M.]]
+[[Category: Kim Y]]
-[[Category: Bzip]]
+[[Category: Podust LM]]
-[[Category: Protein-dna complex]]
-[[Category: Transcription-dna complex]]