1jj6: Difference between revisions

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[[Image:1jj6.png|left|200px]]


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==Testing the Water-Mediated Hin Recombinase DNA Recognition by Systematic Mutations.==
The line below this paragraph, containing "STRUCTURE_1jj6", creates the "Structure Box" on the page.
<StructureSection load='1jj6' size='340' side='right'caption='[[1jj6]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1jj6]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JJ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JJ6 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5IU:5-IODO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>5IU</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
{{STRUCTURE_1jj6| PDB=1jj6 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jj6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jj6 OCA], [https://pdbe.org/1jj6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jj6 RCSB], [https://www.ebi.ac.uk/pdbsum/1jj6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jj6 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HIN_SALTY HIN_SALTY] A DNA fragment of approximately 900 base pairs, adjacent to the fljB (H2) gene, which specifies the synthesis of phase-2 flagellin, can exist in either orientation with respect to fljB. The orientation of the inversion region controls expression of fljB. The hin gene occupies about two-thirds of the inversion region; it is required for the inversion of the fljB controlling region.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jj/1jj6_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jj6 ConSurf].
<div style="clear:both"></div>


===Testing the Water-Mediated Hin Recombinase DNA Recognition by Systematic Mutations.===
==See Also==
 
*[[Resolvase 3D structures|Resolvase 3D structures]]
 
__TOC__
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</StructureSection>
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[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 11847127 is the PubMed ID number.
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
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[[Category: Chiu TK]]
{{ABSTRACT_PUBMED_11847127}}
[[Category: Dickerson RE]]
 
[[Category: Johnson RC]]
==About this Structure==
[[Category: Sohn C]]
1JJ6 is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JJ6 OCA].
 
==Reference==
Testing water-mediated DNA recognition by the Hin recombinase., Chiu TK, Sohn C, Dickerson RE, Johnson RC, EMBO J. 2002 Feb 15;21(4):801-14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11847127 11847127]
[[Category: Single protein]]
[[Category: Chiu, T K.]]
[[Category: Dickerson, R E.]]
[[Category: Johnson, R C.]]
[[Category: Sohn, C.]]
[[Category: Hin recombinase]]
[[Category: I5]]
[[Category: Protein-dna complex]]
[[Category: Water-mediated recognition]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 20:19:31 2008''

Latest revision as of 10:39, 7 February 2024

Testing the Water-Mediated Hin Recombinase DNA Recognition by Systematic Mutations.Testing the Water-Mediated Hin Recombinase DNA Recognition by Systematic Mutations.

Structural highlights

1jj6 is a 3 chain structure with sequence from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HIN_SALTY A DNA fragment of approximately 900 base pairs, adjacent to the fljB (H2) gene, which specifies the synthesis of phase-2 flagellin, can exist in either orientation with respect to fljB. The orientation of the inversion region controls expression of fljB. The hin gene occupies about two-thirds of the inversion region; it is required for the inversion of the fljB controlling region.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1jj6, resolution 2.30Å

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