1jhs: Difference between revisions

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[[Image:1jhs.png|left|200px]]


{{STRUCTURE_1jhs|  PDB=1jhs  |  SCENE=  }}
==Protein Mog1 E65A mutant==
 
<StructureSection load='1jhs' size='340' side='right'caption='[[1jhs]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
===Protein Mog1 E65A mutant===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1jhs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JHS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JHS FirstGlance]. <br>
{{ABSTRACT_PUBMED_11509570}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jhs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jhs OCA], [https://pdbe.org/1jhs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jhs RCSB], [https://www.ebi.ac.uk/pdbsum/1jhs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jhs ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1jhs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JHS OCA].  
== Function ==
 
[https://www.uniprot.org/uniprot/MOG1_YEAST MOG1_YEAST] Involved in the Ran-GTPase system for nuclear protein import and poly(A)+ mRNA export.<ref>PMID:9860978</ref> <ref>PMID:11509570</ref>  
==Reference==
== Evolutionary Conservation ==
<ref group="xtra">PMID:011509570</ref><references group="xtra"/>
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jh/1jhs_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jhs ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Baker, R P.]]
[[Category: Baker RP]]
[[Category: Corbett, A H.]]
[[Category: Corbett AH]]
[[Category: Ecclestone, J F.]]
[[Category: Ecclestone JF]]
[[Category: Harreman, M T.]]
[[Category: Harreman MT]]
[[Category: Stewart, M.]]
[[Category: Stewart M]]
[[Category: Gene regulation]]
[[Category: Gsp1]]
[[Category: Nuclear-protein import]]

Latest revision as of 10:39, 7 February 2024

Protein Mog1 E65A mutantProtein Mog1 E65A mutant

Structural highlights

1jhs is a 1 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MOG1_YEAST Involved in the Ran-GTPase system for nuclear protein import and poly(A)+ mRNA export.[1] [2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Oki M, Nishimoto T. A protein required for nuclear-protein import, Mog1p, directly interacts with GTP-Gsp1p, the Saccharomyces cerevisiae ran homologue. Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15388-93. PMID:9860978
  2. Baker RP, Harreman MT, Eccleston JF, Corbett AH, Stewart M. Interaction between Ran and Mog1 is required for efficient nuclear protein import. J Biol Chem. 2001 Nov 2;276(44):41255-62. Epub 2001 Aug 16. PMID:11509570 doi:10.1074/jbc.M106060200

1jhs, resolution 1.90Å

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