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==Signal Recognition Particle conserved GTPase domain from A. ambivalens== | |||
<StructureSection load='1j8m' size='340' side='right'caption='[[1j8m]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1j8m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acidianus_ambivalens Acidianus ambivalens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J8M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J8M FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j8m OCA], [https://pdbe.org/1j8m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j8m RCSB], [https://www.ebi.ac.uk/pdbsum/1j8m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j8m ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SRP54_ACIAM SRP54_ACIAM] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY (By similarity). | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j8/1j8m_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j8m ConSurf]. | |||
<div style="clear:both"></div> | |||
== | ==See Also== | ||
*[[Signal recognition particle 3D structures|Signal recognition particle 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[ | |||
< | |||
[[Category: Acidianus ambivalens]] | [[Category: Acidianus ambivalens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Moll | [[Category: Moll R]] | ||
[[Category: Montoya | [[Category: Montoya G]] | ||
[[Category: Schafer | [[Category: Schafer G]] | ||
[[Category: Sinning | [[Category: Sinning I]] | ||
[[Category: | [[Category: Te Kaat K]] | ||
Latest revision as of 10:37, 7 February 2024
Signal Recognition Particle conserved GTPase domain from A. ambivalensSignal Recognition Particle conserved GTPase domain from A. ambivalens
Structural highlights
FunctionSRP54_ACIAM Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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