1in4: Difference between revisions

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-[[Image:1in4.png|left|200px]]
-{{STRUCTURE_1in4|  PDB=1in4  |  SCENE=  }}
+==THERMOTOGA MARITIMA RUVB HOLLIDAY JUNCTION BRANCH MIGRATION MOTOR==
+<StructureSection load='1in4' size='340' side='right'caption='[[1in4]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-===THERMOTOGA MARITIMA RUVB HOLLIDAY JUNCTION BRANCH MIGRATION MOTOR===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1in4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IN4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IN4 FirstGlance]. <br>
-{{ABSTRACT_PUBMED_11478862}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=HEZ:HEXANE-1,6-DIOL'>HEZ</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1in4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1in4 OCA], [https://pdbe.org/1in4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1in4 RCSB], [https://www.ebi.ac.uk/pdbsum/1in4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1in4 ProSAT]</span></td></tr>
-[[1in4]] is a 1 chain structure of [[Helicase]] with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IN4 OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/RUVB_THEMA RUVB_THEMA] The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/in/1in4_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1in4 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Helicase|Helicase]]
+*[[Helicase 3D structures|Helicase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:011478862</ref><references group="xtra"/>
+[[Category: Large Structures]]
 [[Category: Thermotoga maritima]]
-[[Category: Putnam, C D.]]
+[[Category: Putnam CD]]
-[[Category: Tainer, J A.]]
+[[Category: Tainer JA]]
-[[Category: Aaa+-class atpase]]
-[[Category: Arginine finger]]
-[[Category: Atp hydrolysis]]
-[[Category: Branch migration]]
-[[Category: Dna binding protein]]
-[[Category: Dna translocase]]
-[[Category: Holliday junction]]
-[[Category: Sensor 1]]
-[[Category: Sensor 2]]
-[[Category: Walker some]]
-[[Category: Walker b]]
-[[Category: Winged-helix domain]]