1ijw: Difference between revisions

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[[Image:1ijw.png|left|200px]]


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==Testing the Water-Mediated Hin Recombinase DNA Recognition by Systematic Mutations.==
The line below this paragraph, containing "STRUCTURE_1ijw", creates the "Structure Box" on the page.
<StructureSection load='1ijw' size='340' side='right'caption='[[1ijw]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1ijw]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IJW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IJW FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CBR:5-BROMO-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>CBR</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
{{STRUCTURE_1ijw| PDB=1ijw |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ijw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ijw OCA], [https://pdbe.org/1ijw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ijw RCSB], [https://www.ebi.ac.uk/pdbsum/1ijw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ijw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HIN_SALTY HIN_SALTY] A DNA fragment of approximately 900 base pairs, adjacent to the fljB (H2) gene, which specifies the synthesis of phase-2 flagellin, can exist in either orientation with respect to fljB. The orientation of the inversion region controls expression of fljB. The hin gene occupies about two-thirds of the inversion region; it is required for the inversion of the fljB controlling region.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ij/1ijw_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ijw ConSurf].
<div style="clear:both"></div>


===Testing the Water-Mediated Hin Recombinase DNA Recognition by Systematic Mutations.===
==See Also==
 
*[[Resolvase 3D structures|Resolvase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_11847127}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 11847127 is the PubMed ID number.
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
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[[Category: Chiu TK]]
{{ABSTRACT_PUBMED_11847127}}
[[Category: Dickerson RE]]
 
[[Category: Johnson RC]]
==About this Structure==
[[Category: Sohn C]]
1IJW is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IJW OCA].
 
==Reference==
Testing water-mediated DNA recognition by the Hin recombinase., Chiu TK, Sohn C, Dickerson RE, Johnson RC, EMBO J. 2002 Feb 15;21(4):801-14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11847127 11847127]
[[Category: Single protein]]
[[Category: Chiu, T K.]]
[[Category: Dickerson, R E.]]
[[Category: Johnson, R C.]]
[[Category: Sohn, C.]]
[[Category: Br18]]
[[Category: Hin recombinase]]
[[Category: Protein-dna complex]]
[[Category: Water-mediated recognition]]
 
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