1ih4: Difference between revisions

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[[Image:1ih4.gif|left|200px]]


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==Multi-Conformation Crystal Structure of GGm5CGCC==
The line below this paragraph, containing "STRUCTURE_1ih4", creates the "Structure Box" on the page.
<StructureSection load='1ih4' size='340' side='right'caption='[[1ih4]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1ih4]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IH4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IH4 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene></td></tr>
{{STRUCTURE_1ih4|  PDB=1ih4 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ih4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ih4 OCA], [https://pdbe.org/1ih4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ih4 RCSB], [https://www.ebi.ac.uk/pdbsum/1ih4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ih4 ProSAT]</span></td></tr>
 
</table>
'''Multi-Conformation Crystal Structure of GGm5CGCC'''
__TOC__
 
</StructureSection>
 
[[Category: Large Structures]]
==Overview==
[[Category: Henderson K]]
The transition between B- and A-DNA was first observed nearly 50 years ago. We have now mapped this transformation through a set of single-crystal structures of the sequence d(GGCGCC)2, with various intermediates being trapped by methylating or brominating the cytosine bases. The resulting pathway progresses through 13 conformational steps, with a composite structure that pairs A-nucleotides with complementary B-nucleotides serving as a distinct transition intermediate. The details of each step in the conversion of B- to A-DNA are thus revealed at the atomic level, placing intermediates for this and other sequences in the context of a common pathway.
[[Category: Ho PS]]
 
[[Category: Vargason JM]]
==About this Structure==
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IH4 OCA].  
 
==Reference==
A crystallographic map of the transition from B-DNA to A-DNA., Vargason JM, Henderson K, Ho PS, Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7265-70. Epub 2001 Jun 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11390969 11390969]
[[Category: Henderson, K.]]
[[Category: Ho, P S.]]
[[Category: Vargason, J M.]]
[[Category: B to a dna transition]]
[[Category: Dna transition]]
[[Category: Structural transition]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 19:59:37 2008''

Latest revision as of 10:35, 7 February 2024

Multi-Conformation Crystal Structure of GGm5CGCCMulti-Conformation Crystal Structure of GGm5CGCC

Structural highlights

1ih4 is a 8 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

1ih4, resolution 1.90Å

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