1i33: Difference between revisions

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[[Image:1i33.png|left|200px]]


{{STRUCTURE_1i33|  PDB=1i33  |  SCENE=  }}
==LEISHMANIA MEXICANA GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH INHIBITORS==
 
<StructureSection load='1i33' size='340' side='right'caption='[[1i33]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
===LEISHMANIA MEXICANA GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH INHIBITORS===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1i33]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_mexicana Leishmania mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I33 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I33 FirstGlance]. <br>
{{ABSTRACT_PUBMED_11371162}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TND:N-1,2,3,4-TETRAHYDRONAPHTH-1-YL-2-[3,5-DIMETHOXYBENZAMIDO]-2-DEOXY-ADENOSINE'>TND</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i33 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i33 OCA], [https://pdbe.org/1i33 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i33 RCSB], [https://www.ebi.ac.uk/pdbsum/1i33 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i33 ProSAT]</span></td></tr>
[[1i33]] is a 6 chain structure of [[Aldehyde dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Leishmania_mexicana Leishmania mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I33 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/G3PG_LEIME G3PG_LEIME]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i3/1i33_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i33 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Aldehyde dehydrogenase|Aldehyde dehydrogenase]]
*[[Aldehyde dehydrogenase 3D structures|Aldehyde dehydrogenase 3D structures]]
 
*[[Glyceraldehyde-3-phosphate dehydrogenase 3D structures|Glyceraldehyde-3-phosphate dehydrogenase 3D structures]]
==Reference==
__TOC__
<ref group="xtra">PMID:011371162</ref><references group="xtra"/>
</StructureSection>
[[Category: Large Structures]]
[[Category: Leishmania mexicana]]
[[Category: Leishmania mexicana]]
[[Category: Bressi, J C.]]
[[Category: Bressi JC]]
[[Category: Gelb, M H.]]
[[Category: Gelb MH]]
[[Category: Hol, W G.J.]]
[[Category: Hol WGJ]]
[[Category: Kennedy, K J.]]
[[Category: Kennedy KJ]]
[[Category: Suresh, S.]]
[[Category: Suresh S]]
[[Category: Verlinde, C L.M J.]]
[[Category: Verlinde CLMJ]]
[[Category: Dehydrogenase]]
[[Category: Enzyme]]
[[Category: Oxidoreductase]]

Latest revision as of 10:32, 7 February 2024

LEISHMANIA MEXICANA GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH INHIBITORSLEISHMANIA MEXICANA GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH INHIBITORS

Structural highlights

1i33 is a 6 chain structure with sequence from Leishmania mexicana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

G3PG_LEIME

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1i33, resolution 3.00Å

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OCA