1i27: Difference between revisions

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-{{Seed}}
-[[Image:1i27.png|left|200px]]
-<!--
+==CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF THE RAP74 SUBUNIT OF HUMAN TRANSCRIPTION FACTOR IIF (TFIIF)==
-The line below this paragraph, containing "STRUCTURE_1i27", creates the "Structure Box" on the page.
+<StructureSection load='1i27' size='340' side='right'caption='[[1i27]], [[Resolution|resolution]] 1.02&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1i27]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I27 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I27 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.02&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-{{STRUCTURE_1i27|  PDB=1i27  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i27 OCA], [https://pdbe.org/1i27 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i27 RCSB], [https://www.ebi.ac.uk/pdbsum/1i27 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i27 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/T2FA_HUMAN T2FA_HUMAN] TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.<ref>PMID:10428810</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i2/1i27_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i27 ConSurf].
+<div style="clear:both"></div>
-===CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF THE RAP74 SUBUNIT OF HUMAN TRANSCRIPTION FACTOR IIF (TFIIF)===
+==See Also==
+*[[Transcription initiation factors 3D structures|Transcription initiation factors 3D structures]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_11248041}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 11248041 is the PubMed ID number.
+</StructureSection>
--->
-{{ABSTRACT_PUBMED_11248041}}
-==About this Structure==
-I27 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I27 OCA].
-==Reference==
-Crystal structure of the C-terminal domain of the RAP74 subunit of human transcription factor IIF., Kamada K, De Angelis J, Roeder RG, Burley SK, Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3115-20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11248041 11248041]
 [[Category: Homo sapiens]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Angelis, J De.]]
+[[Category: Burley SK]]
-[[Category: Burley, S K.]]
+[[Category: De Angelis J]]
-[[Category: Kamada, K.]]
+[[Category: Kamada K]]
-[[Category: Roeder, R G.]]
+[[Category: Roeder RG]]
-[[Category: General transcription factor]]
-[[Category: Rap30]]
-[[Category: Rap74]]
-[[Category: Rna polymerase ii]]
-[[Category: Tfiif]]
-[[Category: Winged-helix domain]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 10:18:12 2008''