1hxt: Difference between revisions

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{{Seed}}
[[Image:1hxt.png|left|200px]]


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==OMPF PORIN MUTANT NQAAA==
The line below this paragraph, containing "STRUCTURE_1hxt", creates the "Structure Box" on the page.
<StructureSection load='1hxt' size='340' side='right'caption='[[1hxt]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1hxt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HXT FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene></td></tr>
{{STRUCTURE_1hxt| PDB=1hxt |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hxt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hxt OCA], [https://pdbe.org/1hxt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hxt RCSB], [https://www.ebi.ac.uk/pdbsum/1hxt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hxt ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/OMPF_ECOLI OMPF_ECOLI] Forms pores that allow passive diffusion of small molecules across the outer membrane. It is also a receptor for the bacteriophage T2.<ref>PMID:19721064</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hx/1hxt_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hxt ConSurf].
<div style="clear:both"></div>


===OMPF PORIN MUTANT NQAAA===
==See Also==
 
*[[Porin 3D structures|Porin 3D structures]]
 
== References ==
<!--
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_11371193}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 11371193 is the PubMed ID number.
</StructureSection>
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{{ABSTRACT_PUBMED_11371193}}
 
==About this Structure==
1HXT is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXT OCA].
 
==Reference==
<ref group="xtra">PMID:11371193</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Phale, P S.]]
[[Category: Large Structures]]
[[Category: Phale, V P.]]
[[Category: Phale PS]]
[[Category: Philippsen, A.]]
[[Category: Phale VP]]
[[Category: Rosenbusch, J P.]]
[[Category: Philippsen A]]
[[Category: Schirmer, T.]]
[[Category: Rosenbusch JP]]
[[Category: Widmer, C.]]
[[Category: Schirmer T]]
[[Category: Beta barrel]]
[[Category: Widmer C]]
[[Category: Membrane protein]]
[[Category: Porin]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 13:29:54 2009''

Latest revision as of 10:31, 7 February 2024

OMPF PORIN MUTANT NQAAAOMPF PORIN MUTANT NQAAA

Structural highlights

1hxt is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.4Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

OMPF_ECOLI Forms pores that allow passive diffusion of small molecules across the outer membrane. It is also a receptor for the bacteriophage T2.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. Duval V, Nicoloff H, Levy SB. Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. Antimicrob Agents Chemother. 2009 Nov;53(11):4944-8. doi: 10.1128/AAC.00787-09., Epub 2009 Aug 31. PMID:19721064 doi:10.1128/AAC.00787-09

1hxt, resolution 2.40Å

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