1hxt: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
No edit summary
No edit summary
 
(8 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:1hxt.png|left|200px]]


{{STRUCTURE_1hxt|  PDB=1hxt  |  SCENE=  }}
==OMPF PORIN MUTANT NQAAA==
 
<StructureSection load='1hxt' size='340' side='right'caption='[[1hxt]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
===OMPF PORIN MUTANT NQAAA===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1hxt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HXT FirstGlance]. <br>
{{ABSTRACT_PUBMED_11371193}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hxt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hxt OCA], [https://pdbe.org/1hxt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hxt RCSB], [https://www.ebi.ac.uk/pdbsum/1hxt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hxt ProSAT]</span></td></tr>
[[1hxt]] is a 1 chain structure of [[Porin]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXT OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/OMPF_ECOLI OMPF_ECOLI] Forms pores that allow passive diffusion of small molecules across the outer membrane. It is also a receptor for the bacteriophage T2.<ref>PMID:19721064</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hx/1hxt_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hxt ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Porin|Porin]]
*[[Porin 3D structures|Porin 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:011371193</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Phale, P S.]]
[[Category: Large Structures]]
[[Category: Phale, V P.]]
[[Category: Phale PS]]
[[Category: Philippsen, A.]]
[[Category: Phale VP]]
[[Category: Rosenbusch, J P.]]
[[Category: Philippsen A]]
[[Category: Schirmer, T.]]
[[Category: Rosenbusch JP]]
[[Category: Widmer, C.]]
[[Category: Schirmer T]]
[[Category: Beta barrel]]
[[Category: Widmer C]]
[[Category: Membrane protein]]
[[Category: Porin]]

Latest revision as of 10:31, 7 February 2024

OMPF PORIN MUTANT NQAAAOMPF PORIN MUTANT NQAAA

Structural highlights

1hxt is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.4Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

OMPF_ECOLI Forms pores that allow passive diffusion of small molecules across the outer membrane. It is also a receptor for the bacteriophage T2.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. Duval V, Nicoloff H, Levy SB. Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. Antimicrob Agents Chemother. 2009 Nov;53(11):4944-8. doi: 10.1128/AAC.00787-09., Epub 2009 Aug 31. PMID:19721064 doi:10.1128/AAC.00787-09

1hxt, resolution 2.40Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA