1hqm: Difference between revisions

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-{{Seed}}
-[[Image:1hqm.png|left|200px]]
-<!--
+==CRYSTAL STRUCTURE OF THERMUS AQUATICUS CORE RNA POLYMERASE-INCLUDES COMPLETE STRUCTURE WITH SIDE-CHAINS (EXCEPT FOR DISORDERED REGIONS)-FURTHER REFINED FROM ORIGINAL DEPOSITION-CONTAINS ADDITIONAL SEQUENCE INFORMATION==
-The line below this paragraph, containing "STRUCTURE_1hqm", creates the "Structure Box" on the page.
+<StructureSection load='1hqm' size='340' side='right'caption='[[1hqm]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1hqm]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ddq 1ddq]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HQM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HQM FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-{{STRUCTURE_1hqm|  PDB=1hqm  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hqm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hqm OCA], [https://pdbe.org/1hqm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hqm RCSB], [https://www.ebi.ac.uk/pdbsum/1hqm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hqm ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/RPOA_THEAQ RPOA_THEAQ]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hq/1hqm_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hqm ConSurf].
+<div style="clear:both"></div>
-===CRYSTAL STRUCTURE OF THERMUS AQUATICUS CORE RNA POLYMERASE-INCLUDES COMPLETE STRUCTURE WITH SIDE-CHAINS (EXCEPT FOR DISORDERED REGIONS)-FURTHER REFINED FROM ORIGINAL DEPOSITION-CONTAINS ADDITIONAL SEQUENCE INFORMATION===
+==See Also==
+*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_11158566}}, adds the Publication Abstract to the page
+[[Category: Large Structures]]
-(as it appears on PubMed at http://www.pubmed.gov), where 11158566 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_11158566}}
-==About this Structure==
-HQM is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ddq 1ddq]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HQM OCA].
-==Reference==
-Bacterial RNA polymerase subunit omega and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly., Minakhin L, Bhagat S, Brunning A, Campbell EA, Darst SA, Ebright RH, Severinov K, Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):892-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11158566 11158566]
-[[Category: DNA-directed RNA polymerase]]
-[[Category: Protein complex]]
 [[Category: Thermus aquaticus]]
-[[Category: Bhagat, S.]]
+[[Category: Bhagat S]]
-[[Category: Brunning, A.]]
+[[Category: Brunning A]]
-[[Category: Campbell, E A.]]
+[[Category: Campbell EA]]
-[[Category: Darst, S A.]]
+[[Category: Darst SA]]
-[[Category: Ebright, R H.]]
+[[Category: Ebright RH]]
-[[Category: Minakhin, L.]]
+[[Category: Minakhin L]]
-[[Category: Severinov, K.]]
+[[Category: Severinov K]]
-[[Category: 3d-structure]]
-[[Category: Dna-directed rna polymerase]]
-[[Category: Transcription]]
-[[Category: Transferase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 08:32:54 2008''