1ho4: Difference between revisions

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-[[Image:1ho4.png|left|200px]]
-{{STRUCTURE_1ho4|  PDB=1ho4  |  SCENE=  }}
+==CRYSTAL STRUCTURE OF PYRIDOXINE 5'-PHOSPHATE SYNTHASE IN COMPLEX WITH PYRIDOXINE 5'-PHOSPHATE AND INORGANIC PHOSPHATE==
+<StructureSection load='1ho4' size='340' side='right'caption='[[1ho4]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-===CRYSTAL STRUCTURE OF PYRIDOXINE 5'-PHOSPHATE SYNTHASE IN COMPLEX WITH PYRIDOXINE 5'-PHOSPHATE AND INORGANIC PHOSPHATE===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1ho4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HO4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HO4 FirstGlance]. <br>
-{{ABSTRACT_PUBMED_11286891}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=PXP:PYRIDOXINE-5-PHOSPHATE'>PXP</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ho4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ho4 OCA], [https://pdbe.org/1ho4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ho4 RCSB], [https://www.ebi.ac.uk/pdbsum/1ho4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ho4 ProSAT]</span></td></tr>
-[[1ho4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HO4 OCA].
+</table>
+== Function ==
-==Reference==
+[https://www.uniprot.org/uniprot/PDXJ_ECOLI PDXJ_ECOLI] Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.<ref>PMID:10225425</ref>
-<ref group="xtra">PMID:011286891</ref><references group="xtra"/>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ho/1ho4_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ho4 ConSurf].
+<div style="clear:both"></div>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Escherichia coli]]
-[[Category: Clausen, T.]]
+[[Category: Large Structures]]
-[[Category: Garrido-Franco, M.]]
+[[Category: Clausen T]]
-[[Category: Huber, R.]]
+[[Category: Garrido-Franco M]]
-[[Category: Laber, B.]]
+[[Category: Huber R]]
-[[Category: Biosynthetic protein]]
+[[Category: Laber B]]
-[[Category: Enzyme-product complex]]
-[[Category: Open-closed transition]]
-[[Category: Tim barrel]]
-[[Category: Water channel]]