1hnb: Difference between revisions

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[[Image:1hnb.png|left|200px]]


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==CRYSTAL STRUCTURE OF HUMAN CLASS MU GLUTATHIONE TRANSFERASE GSTM2-2: EFFECTS OF LATTICE PACKING ON CONFORMATIONAL HETEROGENEITY==
The line below this paragraph, containing "STRUCTURE_1hnb", creates the "Structure Box" on the page.
<StructureSection load='1hnb' size='340' side='right'caption='[[1hnb]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1hnb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HNB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HNB FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDN:GLUTATHIONE+S-(2,4+DINITROBENZENE)'>GDN</scene></td></tr>
{{STRUCTURE_1hnb| PDB=1hnb |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hnb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hnb OCA], [https://pdbe.org/1hnb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hnb RCSB], [https://www.ebi.ac.uk/pdbsum/1hnb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hnb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GSTM2_HUMAN GSTM2_HUMAN] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.<ref>PMID:16549767</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hn/1hnb_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hnb ConSurf].
<div style="clear:both"></div>


===CRYSTAL STRUCTURE OF HUMAN CLASS MU GLUTATHIONE TRANSFERASE GSTM2-2: EFFECTS OF LATTICE PACKING ON CONFORMATIONAL HETEROGENEITY===
==See Also==
 
*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]]
 
== References ==
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(as it appears on PubMed at http://www.pubmed.gov), where 8182750 is the PubMed ID number.
</StructureSection>
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{{ABSTRACT_PUBMED_8182750}}
 
==About this Structure==
1HNB is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HNB OCA].
 
==Reference==
<ref group="xtra">PMID:8182750</ref><references group="xtra"/>
[[Category: Glutathione transferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Allison, T J.]]
[[Category: Large Structures]]
[[Category: Chandross, R J.]]
[[Category: Allison TJ]]
[[Category: Kretsinger, R H.]]
[[Category: Chandross RJ]]
[[Category: Penington, C J.]]
[[Category: Kretsinger RH]]
[[Category: Raghunathan, S.]]
[[Category: Penington CJ]]
[[Category: Rule, G S.]]
[[Category: Raghunathan S]]
 
[[Category: Rule GS]]
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