1hlv: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:1hlv.png|left|200px]]
-{{STRUCTURE_1hlv|  PDB=1hlv  |  SCENE=  }}
+==CRYSTAL STRUCTURE OF CENP-B(1-129) COMPLEXED WITH THE CENP-B BOX DNA==
+<StructureSection load='1hlv' size='340' side='right'caption='[[1hlv]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1hlv]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HLV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HLV FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hlv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hlv OCA], [https://pdbe.org/1hlv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hlv RCSB], [https://www.ebi.ac.uk/pdbsum/1hlv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hlv ProSAT], [https://www.topsan.org/Proteins/RSGI/1hlv TOPSAN]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CENPB_HUMAN CENPB_HUMAN] Interacts with centromeric heterochromatin in chromosomes and binds to a specific subset of alphoid satellite DNA, called the CENP-B box. May organize arrays of centromere satellite DNA into a higher-order structure which then directs centromere formation and kinetochore assembly in mammalian chromosomes.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hl/1hlv_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hlv ConSurf].
+<div style="clear:both"></div>
-===CRYSTAL STRUCTURE OF CENP-B(1-129) COMPLEXED WITH THE CENP-B BOX DNA===
+==See Also==
+*[[Centromere protein 3D structure|Centromere protein 3D structure]]
-{{ABSTRACT_PUBMED_11726497}}
+__TOC__
+</StructureSection>
-==About this Structure==
-[[1hlv]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HLV OCA].
-==Reference==
-<ref group="xtra">PMID:011726497</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Fukai, S.]]
+[[Category: Large Structures]]
-[[Category: Ikuta, M.]]
+[[Category: Fukai S]]
-[[Category: Iwahara, J.]]
+[[Category: Ikuta M]]
-[[Category: Kawaguchi, S.]]
+[[Category: Iwahara J]]
-[[Category: Kurumizaka, H.]]
+[[Category: Kawaguchi S]]
-[[Category: Nureki, O.]]
+[[Category: Kurumizaka H]]
-[[Category: Okazaki, T.]]
+[[Category: Nureki O]]
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+[[Category: Okazaki T]]
-[[Category: Tanaka, Y.]]
+[[Category: Tanaka Y]]
-[[Category: Yokoyama, S.]]
+[[Category: Yokoyama S]]
-[[Category: Dna binding protein-dna complex]]
-[[Category: Helix-turn-helix]]
-[[Category: Protein-dna complex]]
-[[Category: Riken structural genomics/proteomics initiative]]
-[[Category: Rsgi]]
-[[Category: Structural genomic]]