1hlp: Difference between revisions

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[[Image:1hlp.png|left|200px]]


{{STRUCTURE_1hlp|  PDB=1hlp  |  SCENE=  }}
==STRUCTURAL FEATURES STABILIZING HALOPHILIC MALATE DEHYDROGENASE FROM AN ARCHAEBACTERIUM==
 
<StructureSection load='1hlp' size='340' side='right'caption='[[1hlp]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
===STRUCTURAL FEATURES STABILIZING HALOPHILIC MALATE DEHYDROGENASE FROM AN ARCHAEBACTERIUM===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1hlp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HLP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HLP FirstGlance]. <br>
{{ABSTRACT_PUBMED_17812611}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hlp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hlp OCA], [https://pdbe.org/1hlp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hlp RCSB], [https://www.ebi.ac.uk/pdbsum/1hlp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hlp ProSAT]</span></td></tr>
[[1hlp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HLP OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/MDH_HALMA MDH_HALMA] Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_00487]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hl/1hlp_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hlp ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Johnson sandbox 1|Johnson sandbox 1]]
*[[Malate Dehydrogenase 3D structures|Malate Dehydrogenase 3D structures]]
*[[Malate dehydrogenase|Malate dehydrogenase]]
__TOC__
 
</StructureSection>
==Reference==
<ref group="xtra">PMID:017812611</ref><references group="xtra"/>
[[Category: Haloarcula marismortui]]
[[Category: Haloarcula marismortui]]
[[Category: Malate dehydrogenase]]
[[Category: Large Structures]]
[[Category: Dym, O.]]
[[Category: Dym O]]
[[Category: Mevarech, M.]]
[[Category: Mevarech M]]
[[Category: Sussman, J L.]]
[[Category: Sussman JL]]
[[Category: Dehydrogenase]]
[[Category: Halophilic]]

Latest revision as of 10:28, 7 February 2024

STRUCTURAL FEATURES STABILIZING HALOPHILIC MALATE DEHYDROGENASE FROM AN ARCHAEBACTERIUMSTRUCTURAL FEATURES STABILIZING HALOPHILIC MALATE DEHYDROGENASE FROM AN ARCHAEBACTERIUM

Structural highlights

1hlp is a 2 chain structure with sequence from Haloarcula marismortui. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MDH_HALMA Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_00487]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1hlp, resolution 3.20Å

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