1hjp: Difference between revisions

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-[[Image:1hjp.png|left|200px]]
-{{STRUCTURE_1hjp|  PDB=1hjp  |  SCENE=  }}
+==HOLLIDAY JUNCTION BINDING PROTEIN RUVA FROM E. COLI==
+<StructureSection load='1hjp' size='340' side='right'caption='[[1hjp]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1hjp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HJP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HJP FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hjp OCA], [https://pdbe.org/1hjp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hjp RCSB], [https://www.ebi.ac.uk/pdbsum/1hjp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hjp ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/RUVA_ECOLI RUVA_ECOLI] The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. Binds both single- and double-stranded DNA (dsDNA). Binds preferentially to supercoiled rather than to relaxed dsDNA.<ref>PMID:8433990</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hj/1hjp_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hjp ConSurf].
+<div style="clear:both"></div>
-===HOLLIDAY JUNCTION BINDING PROTEIN RUVA FROM E. COLI===
+==See Also==
+*[[Helicase 3D structures|Helicase 3D structures]]
-{{ABSTRACT_PUBMED_9493263}}
+== References ==
+<references/>
-==About this Structure==
+__TOC__
-[[1hjp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HJP OCA].
+</StructureSection>
-==Reference==
-<ref group="xtra">PMID:009493263</ref><references group="xtra"/>
 [[Category: Escherichia coli]]
-[[Category: Ariyoshi, M.]]
+[[Category: Large Structures]]
-[[Category: Iwasaki, H.]]
+[[Category: Ariyoshi M]]
-[[Category: Morikawa, K.]]
+[[Category: Iwasaki H]]
-[[Category: Nishino, T.]]
+[[Category: Morikawa K]]
-[[Category: Shinagawa, H.]]
+[[Category: Nishino T]]
-[[Category: Dna recombination]]
+[[Category: Shinagawa H]]
-[[Category: Dna repair]]
-[[Category: Holliday junction binding]]