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[[Image:1gle.png|left|200px]]


{{STRUCTURE_1gle|  PDB=1gle  |  SCENE=  }}
==CATION PROMOTED ASSOCIATION (CPA) OF A REGULATORY AND TARGET PROTEIN IS CONTROLLED BY PHOSPHORYLATION==
 
<StructureSection load='1gle' size='340' side='right'caption='[[1gle]], [[Resolution|resolution]] 2.94&Aring;' scene=''>
===CATION PROMOTED ASSOCIATION (CPA) OF A REGULATORY AND TARGET PROTEIN IS CONTROLLED BY PHOSPHORYLATION===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1gle]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GLE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GLE FirstGlance]. <br>
{{ABSTRACT_PUBMED_8170944}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.94&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=G3H:GLYCERALDEHYDE-3-PHOSPHATE'>G3H</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gle FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gle OCA], [https://pdbe.org/1gle PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gle RCSB], [https://www.ebi.ac.uk/pdbsum/1gle PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gle ProSAT]</span></td></tr>
[[1gle]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GLE OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/PTGA_ECOLI PTGA_ECOLI] The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gl/1gle_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gle ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Glycerol kinase|Glycerol kinase]]
*[[Glycerol kinase|Glycerol kinase]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:008170944</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Feese, M D.]]
[[Category: Large Structures]]
[[Category: Meadow, N D.]]
[[Category: Feese MD]]
[[Category: Pettigrew, D W.]]
[[Category: Meadow ND]]
[[Category: Remington, S J.]]
[[Category: Pettigrew DW]]
[[Category: Roseman, S.]]
[[Category: Remington SJ]]
[[Category: Phosphotransferase]]
[[Category: Roseman S]]

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