1g7v: Difference between revisions

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-[[Image:1g7v.png|left|200px]]
-{{STRUCTURE_1g7v|  PDB=1g7v  |  SCENE=  }}
+==CRYSTAL STRUCTURES OF KDO8P SYNTHASE IN ITS BINARY COMPLEXES WITH THE MECHANISM-BASED INHIBITOR==
+<StructureSection load='1g7v' size='340' side='right'caption='[[1g7v]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-===CRYSTAL STRUCTURES OF KDO8P SYNTHASE IN ITS BINARY COMPLEXES WITH THE MECHANISM-BASED INHIBITOR===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1g7v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G7V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G7V FirstGlance]. <br>
-{{ABSTRACT_PUBMED_11371194}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PAI:{[(2,2-DIHYDROXY-ETHYL)-(2,3,4,5-TETRAHYDROXY-6-PHOSPHONOOXY-HEXYL)-AMINO]-METHYL}-PHOSPHONIC+ACID'>PAI</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g7v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g7v OCA], [https://pdbe.org/1g7v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g7v RCSB], [https://www.ebi.ac.uk/pdbsum/1g7v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g7v ProSAT]</span></td></tr>
-[[1g7v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G7V OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/KDSA_ECOLI KDSA_ECOLI] Synthesis of KDO 8-P which is required for lipid A maturation and cellular growth.[HAMAP-Rule:MF_00056]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g7/1g7v_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g7v ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Aldolase|Aldolase]]
+*[[Kdo-8-phosphate synthase|Kdo-8-phosphate synthase]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:011371194</ref><references group="xtra"/>
-[[Category: 3-deoxy-8-phosphooctulonate synthase]]
 [[Category: Escherichia coli]]
-[[Category: Adir, N.]]
+[[Category: Large Structures]]
-[[Category: Asojo, O A.]]
+[[Category: Adir N]]
-[[Category: Baasov, T.]]
+[[Category: Asojo OA]]
-[[Category: Belakhov, V.]]
+[[Category: Baasov T]]
-[[Category: Friedman, J M.]]
+[[Category: Belakhov V]]
-[[Category: Shoham, Y.]]
+[[Category: Friedman JM]]
-[[Category: Beta-alpha-barrel]]
+[[Category: Shoham Y]]
-[[Category: Lipopolysaccharide]]
-[[Category: Lyase]]