1g3y: Difference between revisions

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[[Image:1g3y.png|left|200px]]


{{STRUCTURE_1g3y| PDB=1g3y | SCENE= }}
==ARG80ALA DTXR==
<StructureSection load='1g3y' size='340' side='right'caption='[[1g3y]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1g3y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Corynebacterium_diphtheriae Corynebacterium diphtheriae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G3Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G3Y FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g3y OCA], [https://pdbe.org/1g3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g3y RCSB], [https://www.ebi.ac.uk/pdbsum/1g3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g3y ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DTXR_CORDI DTXR_CORDI] Iron-binding repressor of the dipheteria toxin gene expression. May serve as a global regulator of gene expression. Represses ripA under iron excess.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g3/1g3y_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g3y ConSurf].
<div style="clear:both"></div>


===ARG80ALA DTXR===
==See Also==
 
*[[Diphtheria toxin repressor|Diphtheria toxin repressor]]
{{ABSTRACT_PUBMED_11320302}}
__TOC__
 
</StructureSection>
==About this Structure==
[[1g3y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Corynebacterium_diphtheriae Corynebacterium diphtheriae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G3Y OCA].
 
==Reference==
<ref group="xtra">PMID:011320302</ref><references group="xtra"/>
[[Category: Corynebacterium diphtheriae]]
[[Category: Corynebacterium diphtheriae]]
[[Category: Goranson-Siekierke, J.]]
[[Category: Large Structures]]
[[Category: Hol, W G.J.]]
[[Category: Goranson-Siekierke J]]
[[Category: Holmes, R K.]]
[[Category: Hol WGJ]]
[[Category: Pohl, E.]]
[[Category: Holmes RK]]
[[Category: Dna-binding protein]]
[[Category: Pohl E]]
[[Category: Dtxr]]
[[Category: Gene regulation]]
[[Category: Iron-dependent regulator]]

Latest revision as of 10:22, 7 February 2024

ARG80ALA DTXRARG80ALA DTXR

Structural highlights

1g3y is a 1 chain structure with sequence from Corynebacterium diphtheriae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.8Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DTXR_CORDI Iron-binding repressor of the dipheteria toxin gene expression. May serve as a global regulator of gene expression. Represses ripA under iron excess.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1g3y, resolution 2.80Å

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