1g0u: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-{{Seed}}
-[[Image:1g0u.png|left|200px]]
-<!--
+==A GATED CHANNEL INTO THE PROTEASOME CORE PARTICLE==
-The line below this paragraph, containing "STRUCTURE_1g0u", creates the "Structure Box" on the page.
+<StructureSection load='1g0u' size='340' side='right'caption='[[1g0u]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1g0u]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G0U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G0U FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-{{STRUCTURE_1g0u|  PDB=1g0u  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g0u OCA], [https://pdbe.org/1g0u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g0u RCSB], [https://www.ebi.ac.uk/pdbsum/1g0u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g0u ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PSA2_YEAST PSA2_YEAST] The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g0/1g0u_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g0u ConSurf].
+<div style="clear:both"></div>
-===A GATED CHANNEL INTO THE PROTEASOME CORE PARTICLE===
+==See Also==
+*[[Proteasome 3D structures|Proteasome 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_11062564}}, adds the Publication Abstract to the page
+[[Category: Large Structures]]
-(as it appears on PubMed at http://www.pubmed.gov), where 11062564 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_11062564}}
-==About this Structure==
-G0U is a 28 chains structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G0U OCA].
-==Reference==
-<ref group="xtra">PMID:11062564</ref><references group="xtra"/>
-[[Category: Proteasome endopeptidase complex]]
 [[Category: Saccharomyces cerevisiae]]
-[[Category: Bajorek, M.]]
+[[Category: Bajorek M]]
-[[Category: Finley, D.]]
+[[Category: Finley D]]
-[[Category: Glickman, M H.]]
+[[Category: Glickman MH]]
-[[Category: Groll, M.]]
+[[Category: Groll M]]
-[[Category: Huber, R.]]
+[[Category: Huber R]]
-[[Category: Kohler, A.]]
+[[Category: Kohler A]]
-[[Category: Moroder, L.]]
+[[Category: Moroder L]]
-[[Category: Rubin, D M.]]
+[[Category: Rubin DM]]
-[[Category: Degradation]]
-[[Category: Ntn-hydrolase]]
-[[Category: Protease]]
-[[Category: Proteasome]]
-[[Category: Ubiquitin]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:31:08 2009''