1fwk: Difference between revisions

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[[Image:1fwk.png|left|200px]]


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==CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ADP==
The line below this paragraph, containing "STRUCTURE_1fwk", creates the "Structure Box" on the page.
<StructureSection load='1fwk' size='340' side='right'caption='[[1fwk]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1fwk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FWK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FWK FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_1fwk|  PDB=1fwk  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fwk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fwk OCA], [https://pdbe.org/1fwk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fwk RCSB], [https://www.ebi.ac.uk/pdbsum/1fwk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fwk ProSAT]</span></td></tr>
 
</table>
===CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ADP===
== Function ==
 
[https://www.uniprot.org/uniprot/KHSE_METJA KHSE_METJA] Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate (By similarity).
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fw/1fwk_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_11188689}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1FWK is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FWK OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fwk ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
<ref group="xtra">PMID:11188689</ref><references group="xtra"/>
</StructureSection>
[[Category: Homoserine kinase]]
[[Category: Large Structures]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Daugherty, M.]]
[[Category: Daugherty M]]
[[Category: Grishin, N V.]]
[[Category: Grishin NV]]
[[Category: Osterman, A L.]]
[[Category: Osterman AL]]
[[Category: Zhang, H.]]
[[Category: Zhang H]]
[[Category: Zhou, T.]]
[[Category: Zhou T]]
[[Category: Kinase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 23:41:10 2009''

Latest revision as of 10:19, 7 February 2024

CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ADPCRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ADP

Structural highlights

1fwk is a 4 chain structure with sequence from Methanocaldococcus jannaschii. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.1Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

KHSE_METJA Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1fwk, resolution 2.10Å

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