1fug: Difference between revisions

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-[[Image:1fug.png|left|200px]]
-{{STRUCTURE_1fug|  PDB=1fug  |  SCENE=  }}
+==S-ADENOSYLMETHIONINE SYNTHETASE==
+<StructureSection load='1fug' size='340' side='right'caption='[[1fug]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
-===S-ADENOSYLMETHIONINE SYNTHETASE===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1fug]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FUG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FUG FirstGlance]. <br>
-{{ABSTRACT_PUBMED_8723769}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fug OCA], [https://pdbe.org/1fug PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fug RCSB], [https://www.ebi.ac.uk/pdbsum/1fug PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fug ProSAT]</span></td></tr>
-==About this Structure==
+</table>
-[[1fug]] is a 2 chain structure of [[S-adenosylmethionine synthetase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FUG OCA].
+== Function ==
+[https://www.uniprot.org/uniprot/METK_ECOLI METK_ECOLI] Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. Is essential for growth.[HAMAP-Rule:MF_00086]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fu/1fug_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fug ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[S-adenosylmethionine synthetase|S-adenosylmethionine synthetase]]
+*[[S-adenosylmethionine synthetase 3D structures|S-adenosylmethionine synthetase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:008723769</ref><ref group="xtra">PMID:011742118</ref><ref group="xtra">PMID:016978047</ref><references group="xtra"/>
 [[Category: Escherichia coli]]
-[[Category: Methionine adenosyltransferase]]
+[[Category: Large Structures]]
-[[Category: Fu, Z.]]
+[[Category: Fu Z]]
-[[Category: Markham, G D.]]
+[[Category: Markham GD]]
-[[Category: Takusagawa, F.]]
+[[Category: Takusagawa F]]
-[[Category: Atp-binding]]
-[[Category: Multigene family]]
-[[Category: One-carbon metabolism]]
-[[Category: Transferase]]