1fsl: Difference between revisions

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New page: left|200px<br /><applet load="1fsl" size="450" color="white" frame="true" align="right" spinBox="true" caption="1fsl, resolution 2.3Å" /> '''FERRIC SOYBEAN LEGHEM...
 
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[[Image:1fsl.jpg|left|200px]]<br /><applet load="1fsl" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1fsl, resolution 2.3&Aring;" />
'''FERRIC SOYBEAN LEGHEMOGLOBIN COMPLEXED WITH NICOTINATE'''<br />


==Overview==
==FERRIC SOYBEAN LEGHEMOGLOBIN COMPLEXED WITH NICOTINATE==
Soybean leghemoglobin a is a small (16 kDa) protein facilitating the, transport of O(2) to respiring N(2)-fixing bacteria at low free-O(2), tension. The crystal structure of soybean ferric leghemoglobin a, nicotinate has been refined at 2.3 A resolution. The final R factor is, 15.8% for 6877 reflections between 6.0 and 2.3 A. The structure of soybean, leghemoglobin a (143 residues) is closely similar to that of lupin, leghemoglobin II (153 residues), the proteins having 82 identical residues, when the sequences are aligned. The new structure provides support for the, conclusion that the unique properties of leghemoglobin arise principally, from a heme pocket considerably larger and more flexible than that of, myoglobin, a strongly ruffled heme group, and a proximal histidine, orientation more favourable to ligand binding.
<StructureSection load='1fsl' size='340' side='right'caption='[[1fsl]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1fsl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Glycine_max Glycine max]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FSL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FSL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NIO:NICOTINIC+ACID'>NIO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fsl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fsl OCA], [https://pdbe.org/1fsl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fsl RCSB], [https://www.ebi.ac.uk/pdbsum/1fsl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fsl ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LGBA_SOYBN LGBA_SOYBN] Provides oxygen to the bacteroids. This role is essential for symbiotic nitrogen fixation.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fs/1fsl_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fsl ConSurf].
<div style="clear:both"></div>


==About this Structure==
==See Also==
1FSL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Glycine_max Glycine max] with HEM and NIO as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1FSL OCA].
*[[Hemoglobin 3D structures|Hemoglobin 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
Structure of ferric soybean leghemoglobin a nicotinate at 2.3 A resolution., Ellis PJ, Appleby CA, Guss JM, Hunter WN, Ollis DL, Freeman HC, Acta Crystallogr D Biol Crystallogr. 1997 May 1;53(Pt 3):302-10. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15299933 15299933]
[[Category: Glycine max]]
[[Category: Glycine max]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Ellis, P.J.]]
[[Category: Ellis PJ]]
[[Category: Freeman, H.C.]]
[[Category: Freeman HC]]
[[Category: Guss, J.M.]]
[[Category: Guss JM]]
[[Category: HEM]]
[[Category: NIO]]
[[Category: heme]]
[[Category: multigene family]]
[[Category: nitrogen fixation]]
[[Category: oxygen transport]]
[[Category: respiratory protein]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 15:14:37 2007''

Latest revision as of 10:18, 7 February 2024

FERRIC SOYBEAN LEGHEMOGLOBIN COMPLEXED WITH NICOTINATEFERRIC SOYBEAN LEGHEMOGLOBIN COMPLEXED WITH NICOTINATE

Structural highlights

1fsl is a 2 chain structure with sequence from Glycine max. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LGBA_SOYBN Provides oxygen to the bacteroids. This role is essential for symbiotic nitrogen fixation.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1fsl, resolution 2.30Å

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