1frb: Difference between revisions

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{{Seed}}
[[Image:1frb.png|left|200px]]


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==FR-1 PROTEIN/NADPH/ZOPOLRESTAT COMPLEX==
The line below this paragraph, containing "STRUCTURE_1frb", creates the "Structure Box" on the page.
<StructureSection load='1frb' size='340' side='right'caption='[[1frb]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1frb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FRB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FRB FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=ZST:3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE+ACETIC+ACID'>ZST</scene></td></tr>
{{STRUCTURE_1frb|  PDB=1frb  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1frb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1frb OCA], [https://pdbe.org/1frb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1frb RCSB], [https://www.ebi.ac.uk/pdbsum/1frb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1frb ProSAT]</span></td></tr>
 
</table>
===FR-1 PROTEIN/NADPH/ZOPOLRESTAT COMPLEX===
== Function ==
 
[https://www.uniprot.org/uniprot/ALD2_MOUSE ALD2_MOUSE]
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fr/1frb_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_7578036}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1FRB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FRB OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1frb ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
1.7 A structure of FR-1, a fibroblast growth factor-induced member of the aldo-keto reductase family, complexed with coenzyme and inhibitor., Wilson DK, Nakano T, Petrash JM, Quiocho FA, Biochemistry. 1995 Nov 7;34(44):14323-30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7578036 7578036]
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Quiocho FA]]
[[Category: Quiocho, F A.]]
[[Category: Wilson DK]]
[[Category: Wilson, D K.]]
[[Category: Tim barrel]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 03:49:39 2008''

Latest revision as of 10:18, 7 February 2024

FR-1 PROTEIN/NADPH/ZOPOLRESTAT COMPLEXFR-1 PROTEIN/NADPH/ZOPOLRESTAT COMPLEX

Structural highlights

1frb is a 1 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.7Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ALD2_MOUSE

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1frb, resolution 1.70Å

Drag the structure with the mouse to rotate

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